“…PSC differentiation protocols have been established for generation of hepatic cells [42–44], intestinal tissue [45], thyroid follicular cells [46], airway epithelial cells [47–49], renal progenitor cells [50, 51], retinal cells [52–55], epithelial stem cells [56], epidermal keratinocytes [57], myeloid cells [58, 59], neurons [34, 60], MSCs [61], and melanocytes [62], among many others. Application of these protocols to cancer patient-derived iPSCs and engineered ESCs should allow research of cancers of these organs.…”