PTB Domains

Abstract

Originally published in: Modular Protein Domains. Edited by Giovanni Cesareni, Mario Gimona, Marius Sudol and Michael Yaffe. Copyright © 2005 Wiley‐VCH Verlag GmbH & Co. KGaA Weinheim. Print ISBN: 3‐527‐30813‐2 The sections in this article are Introduction Function of PTB Domain Proteins Role of PTB Domain Proteins in Tyrosine Kinase Signaling Shc Proteins with PTBI Domains Additional PTB Domain Proteins Involved in Tyrosine Kinase Signaling PTB Domain Proteins That Function Independent of Phosphotyrosine PTB Domain Proteins That Bind APP PTB Domain Proteins That Bind Integrins PTB Domain Proteins That Control Endocytosis PTB Domain Structure Broad Binding Specificity Diverse Modes of Engagement Phospholipid Binding Conclusions