Psychotic Symptoms in an Urban General Medicine Practice

Olfson, Mark; Lewis‐Fernández, Roberto; Weissman, Myrna M.; Feder, Adriana; Gameroff, Marc J.; Pilowsky, Daniel J.; Fuentes, Milton A.

doi:10.1176/appi.ajp.159.8.1412

Cited by 157 publications

(120 citation statements)

References 34 publications

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“…Our finding that subclinical psychotic experiences have a negative impact on the clinical manifestation of depression, both in terms of severity and of development over time, concurs with earlier work in the general population (Olfson et al 2002;van Rossum et al 2011;Wigman et al 2012) as well as in a clinical sample (Perlis et al 2011). In the latter, it was shown that depressed individuals with psychotic experiences responded less well to four consecutive pharmacological interventions.…”

Section: Discussionsupporting

confidence: 91%

Subclinical psychotic experiences and bipolar spectrum features in depression: association with outcome of psychotherapy

Wigman

Abidi

et al. 2013

Psychol. Med.

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Background. Subthreshold psychotic and bipolar experiences are common in major depressive disorder (MDD). However, it is unknown if effectiveness of psychotherapy is altered in depressed patients who display such features compared with those without. The current paper aimed to investigate the impact of the co-presence of subclinical psychotic experiences and subclinical bipolar symptoms on the effectiveness of psychological treatment, alone or in combination with pharmacotherapy.Method. In a naturalistic study, patients with MDD (n = 116) received psychological treatment (cognitive behavioural therapy or interpersonal psychotherapy) alone or in combination with pharmacotherapy. Depression and functioning were assessed six times over 2 years. Lifetime psychotic experiences and bipolar symptoms were assessed at the second time point.Results. Subclinical psychotic experiences predicted more depression over time (β = 0.20, p < 0.002), non-remission [odds ratio (OR) 7.51, p < 0.016] and relapse (OR 3.85, p < 0.034). Subthreshold bipolar symptoms predicted relapse (OR 1.16, p < 0.037).Conclusions. In general, subclinical psychotic experiences have a negative impact on the course and outcome of psychotherapy in MDD. Effects of subclinical bipolar experiences were less prominent.

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Section: Discussionsupporting

confidence: 91%

Subclinical psychotic experiences and bipolar spectrum features in depression: association with outcome of psychotherapy

Wigman

Abidi

et al. 2013

Psychol. Med.

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“…3,13 Studies from the developed world have also indicated that the presence of psychotic symptoms in community samples is associated with significantly more role impairment, higher rates of service use and hospitalization as well as increased rates of suicidal ideation. 4,9 These findings need further replication in large representative community based samples within the African context.…”

Section: Introductionmentioning

confidence: 95%

The prevalence and correlates of hallucinations in a general population sample: findings from the South African Stress and Health Study

Temmingh¹,

Stein²,

Seedat³

et al. 2011

Afr. J. Psych

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“…Thus, the racial/ethnic classification was validated using data collected as part of a distinct study having self-reported racial/ethnic data in 1007 patients followed in one of our clinical sites. 55,56 Using the self-reported data as the gold standard, the sensitivity of the CIS database was 67% for Hispanics and 72% for African Americans, and the specificity was 94% for both Hispanics and African Americans. This misclassification would have resulted in an underrepresentation of the proportion of minority women included in the analysis and biased the results toward the null.…”

Section: Strengths and Limitationsmentioning

confidence: 99%

Racial/Ethnic Disparities in Time to Follow-Up after an Abnormal Mammogram

Press

Carrasquillo

Sciacca³

et al. 2008

Journal of Women's Health

140

111

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Background: Although non-Hispanic white women have an increased risk of developing breast cancer, the disease-specific survival is lower for African American and Hispanic women. Little is known about disparities in follow-up after an abnormal mammogram. The goal of this study was to investigate potential disparities in follow-up after an abnormal mammogram. Methods: A retrospective cohort study of 6722 women with an abnormal mammogram and documented follow-up from January 2000 through December 2002 was performed at an academic medical center in New York City. The outcome was the number of days between the abnormal mammogram and follow-up imaging or biopsy. Cox proportional hazards models were used to assess the effect of race/ethnicity and other potential covariates. Results: The median number of days to diagnostic follow-up after an abnormal mammogram was greater for African American (20 days) and Hispanic (21 days) women compared with non-Hispanic white (14 days) women (p Ͻ 0.001). Racial/ethnic disparities remained significant in a multivariable model controlling for age, Breast Imaging Reporting and Data System (BIRADS) category, insurance status, provider practice location, and median household income. Conclusions: After an abnormal mammogram, African American and Hispanic women had longer times to diagnostic follow-up compared with non-Hispanic white women. Future efforts will focus on identifying the barriers to follow-up so that effective interventions may be implemented.

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Psychotic Symptoms in an Urban General Medicine Practice

Cited by 157 publications

References 34 publications

Subclinical psychotic experiences and bipolar spectrum features in depression: association with outcome of psychotherapy

Subclinical psychotic experiences and bipolar spectrum features in depression: association with outcome of psychotherapy

The prevalence and correlates of hallucinations in a general population sample: findings from the South African Stress and Health Study

Racial/Ethnic Disparities in Time to Follow-Up after an Abnormal Mammogram

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