Psychosomatische Aspekte der Prurigo nodularis

Abstract

Increased levels of psychopathological problems and comorbidities also have been found in other dermatoses; they are not specific for PN. Because all of the research on this topic is cross-sectional, we cannot be sure whether these aspects are etiological factors or consequences of PN or independent comorbidities. Nevertheless, psychosomatic aspects should be considered in diagnosis and treatment of PN patients.

Prurigo Activity Score (PAS): validity and reliability of a new instrument to monitor chronic prurigo

“…Nevertheless, also relationships between items asking different contents could be observed, as for example the significant correlations between the estimated number of lesions and the prurigo activity. High scratch activity (item 7a) resulted in high number of lesions (item 2, r = 0.401), which in turn correlated highly significantly with a low number of healed lesions ( r = 0.251; P < 0.001) as previously described . In addition, intensive scratching increases not only the number of lesions but also the distribution of the lesions throughout the body (high correlation between items 7a and 7b with 4).…”

“…High scratch activity (item 7a) resulted in high number of lesions (item 2, r = 0.401), which in turn correlated highly significantly with a low number of healed lesions (r = 0.251; P < 0.001) as previously described. [25][26][27] In addition, intensive scratching increases not only the number of lesions but also the distribution of the lesions throughout the body (high correlation between items 7a and 7b with 4). In the absence of nodules, plaques and ulcers (item 1a) the number of crusts was lower, which is in agreement with the observation that crusts decrease with lesion healing.…”

Itch and psyche: psychiatric aspects of pruritus

“…It can emerge as the symptom of various dermatological, neurological, psychiatric, and systemic diseases or can transpire independently of a pre‐existing skin disease . PN may be associated with higher psychiatric comorbidity, such as anxiety and depression, compared to healthy controls . A case–control study from Germany reported comparable comorbidity rates in psoriasis patients .…”

Serotonin and interleukin-6: Association with pruritus severity, sleep quality and depression severity in Prurigo Nodularis

“…Whether this manifestation is primary or secondary to repeated traumatic manipulation due to chronic pruritus is still not known (Vaidya and Schwartz, 2008). Although reviews on PN frequently mention psychosomatic aspects, there is little empirical research concerning this subject (Tey et al, 2013;Schneider et al, 2014). Like many chronic skin conditions PN is associated with various psychiatric conditions (Coş kun et al, 2005).…”