Psychosocial life achievements in adults even if they received prophylactic cranial irradiation for acute lymphoblastic leukemia during childhood

Pillon, Marta; Tridello, Gloria; Boaro, Maria Paola; Messina, Chiara; Putti, M. C.; Varotto, Stefania; Petris, Maria Grazia; Scrimin, Sara; Zanesco, Luigi; Rosolen, Angelo; Basso, Giuseppe

doi:10.3109/10428194.2012.710903

Cited by 11 publications

(16 citation statements)

References 35 publications

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“…Among the studies exploring the occupational outcome only of childhood AL survivors, the findings are also heterogeneous. Some studies have reported similar employment rates between survivors and controls [31][32][33], whereas others have reported a lower proportion of employed survivors [4,14], but the inclusion criteria are often restrictive depending on the history of the AL. Several factors could contribute to the favorable employment rate of the survivors in our study.…”

Section: Discussionmentioning

confidence: 94%

“…are clearly differentiated. Many previous studies that have explored the employment status of childhood cancer survivors have reported their results concerning unemployed survivors without differentiating, for example, students or those not working by choice [6,17,20,22,23,31,32]. In our study, active childhood AL survivors (currently on the labor market) were compared to the active general French population to explore the potential difficulties in accessing employment for the survivors who were likely to work.…”

Section: Discussionmentioning

confidence: 97%

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Employment in French young adult survivors of childhood leukemia: an LEA study (for Leucemies de l’Enfant et de l’Adolescent—childhood and adolescent leukemia)

et al. 2016

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 97%

Employment in French young adult survivors of childhood leukemia: an LEA study (for Leucemies de l’Enfant et de l’Adolescent—childhood and adolescent leukemia)

et al. 2016

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“…Studies have demonstrated a variety of educational attainment across survivors of childhood cancer. Results include the following: (1) similar outcomes for both survivors and controls10–16; (2) findings showing significantly poorer educational outcomes for survivors17–20 and (3) findings demonstrating significantly better educational attainment, particularly at university level, for survivors 21 22…”

Section: Introductionmentioning

confidence: 85%

Educational attainment in childhood cancer survivors: a meta-analysis

Thomas¹,

Botting²,

Sutcliffe³

2019

Arch Dis Child

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ObjectiveTo assess differences across educational outcomes in survivors of childhood cancer (CCS) compared with peers.DesignSystematic review and meta-analysis of observational studies.Data sources and study selectionMedline, EMBASE, ERIC, CINAHL and PsycInfo from inception to 1st August 2018. Any peer reviewed, comparative study with a population of any survivor of childhood cancer, from high-economy countries, reporting outcomes on educational attainment, were selected.Results26 studies representing 28 434 CCS, 17 814 matched controls, 6582 siblings and six population studies from 11 high-income countries, which have similar access to education and years of mandatory schooling as reported by the Organisation for Economic Cooperation and Development, were included. CCS were more likely to remain at compulsory level (OR 1.36, 95% CI 1.26 to 1.43) and less likely to complete secondary (OR 0.93, 95% CI 0.87 to 1.0) and tertiary level education (OR 0.87, 95% CI 0.78 to 0.98). They were more likely to require special educational needs (OR 2.47, 95% CI 1.91 to 3.20). Subgroup analyses revealed that survivors, irrespective of central nervous system (CNS) involvement, were less likely to progress onto secondary level compared with cancer-free peers (OR 1.77. 95% CI 1.46 to 2.15; OR 1.19, 95% CI 1.00 to 1.42, respectively). This, however, changed at tertiary level where those with CNS involvement continued to perform worse (OR 0.61, 95% CI 0.55 to 0.68) but those without appeared to perform similarly to their peers (OR 1.12, 95% CI 1.0 to 1.25).ConclusionsCompared with controls, we have elucidated significant differences in educational attainment in survivors. This is sustained across different countries, making it an international issue. CNS involvement plays a key role in educational achievement. Clinicians, teachers and policymakers should be made aware of differences and consider advocating for early educational support for survivors.

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“…Younger attained age at the time of follow-up and more late effects were associated with unstable employment. 94…”

Section: Berbis 2015mentioning

confidence: 99%

Surviving childhood cancer: a systematic review of studies on risk and determinants of adverse socioeconomic outcomes

Frederiksen

Mader

Feychting

et al. 2018

Intl Journal of Cancer

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Substantial improvements in childhood cancer survival have resulted in a steadily increasing population of childhood cancer survivors. Whereas somatic late effects have been assessed in many studies, less is known about the impact of childhood cancer on socioeconomic outcomes in survivors. The aim of this article was to evaluate and summarise the evidence on the socioeconomic conditions of childhood cancer survivors and to identify survivors at particular risk of adverse socioeconomic outcomes. An extensive literature search of three electronic databases was conducted. Of 419 articles identified, 52 met the inclusion criteria. All the selected articles were appraised for quality, and findings were summarised in a narrative synthesis. Childhood cancer survivors were at higher risk of adverse socioeconomic outcomes with regard to educational achievement, income and social security benefits than the general population or a sibling comparison group. The risks for unemployment and a lower occupational position were significantly increased only for survivors of a central nervous system tumour. Notably, survivors of central nervous system tumours, survivors treated with cranial radiotherapy and those diagnosed at younger age independent of cancer type were determinants of particular adverse socioeconomic outcomes. Given the increasing population of childhood cancer survivors, targeted follow-up interventions and support strategies addressing not only the somatic and psychiatric late effects but also the socioeconomic difficulties that some childhood cancer survivors face is of high importance to reduce social inequity, and ensure a high quality of life after childhood cancer.

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Psychosocial life achievements in adults even if they received prophylactic cranial irradiation for acute lymphoblastic leukemia during childhood

Cited by 11 publications

References 35 publications

Employment in French young adult survivors of childhood leukemia: an LEA study (for Leucemies de l’Enfant et de l’Adolescent—childhood and adolescent leukemia)

Employment in French young adult survivors of childhood leukemia: an LEA study (for Leucemies de l’Enfant et de l’Adolescent—childhood and adolescent leukemia)

Educational attainment in childhood cancer survivors: a meta-analysis

Surviving childhood cancer: a systematic review of studies on risk and determinants of adverse socioeconomic outcomes

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