Psychosocial contributors to mental and physical health in patients with systemic lupus erythematosus

Abstract

Objective. To delineate psychosocial and systemic lupus erythematosus (SLE)-related medical factors that contribute to the mental and physical health of SLE patients.Methods.

Quality of life in systemic lupus erythematosus patients during more and less active disease states: Differential contributors to mental and physical health

“…As a group, patients with more active SLE reported clinically significant levels of psychological distress. This finding corroborates previous reports of psychological distress in SLE patients (14), and provides support for a link between psychological distress and disease activity. Some caution should be exercised, however, in interpreting these results, as some items on the SCL-90-R may inflate scores (especially on the somatization subscale) because they assess symptoms that may be due to SLE (e.g., weakness in parts of the body, pain).…”

“…Better mental health for patients during less active disease states was associated with less stress, less emotionoriented coping, and more task-oriented coping. Associations between stress and QoL have been previously reported for SLE patients (14), as have associations with passive coping (emotion) and less When we examined contributors to physical health (PCS) as a function of disease states, emotionoriented coping was the only significant association for patients with more active SLE. More emotionoriented coping was related to better physical health.…”

Stress and Coping Strategies in Systemic Lupus Erythematosus: A Review

“…There are studies on the role of minor stress [14,18,25,27,28,[36][37][38][39] , on major stress [16,17,23] as well as on minor and major stress [15,19,21,24,26] . Among them, 3 studies [36][37][38] , whose the first objective was not the role of stress, will be examined in the next chapter on coping strategies.…”

Influência do estresse psicossocial no lúpus eritematoso sistêmico

“…Embora este não seja um achado suficiente para conclusões definitivas, os autores sugerem que possa ser um indício de que estressores psicossociais estejam realmente relacionados com a atividade inflamatória do LES (39) . Além deste relato, merecem atenção quatro estudos de desenho transversal que observaram uma associação entre estresse e piora do LES, embora nenhum destes a tivesse como objetivo principal (40)(41)(42)(43) . Dois desses estudos visavam avaliar transtornos psiquiá-tricos em pacientes com LES, bem como a sua relação com diversas variáveis clínicas e de estresse psicossocial.…”

“…Embora estressores tenham se associado significativamente com atividade da doença na análise univariada, esta relação não foi confirmada na análise multivariada. Interessante notar que neste estudo os estressores cotidianos correlacionaramse diretamente com sofrimento psicológico (42) . Posteriormente, este mesmo grupo avaliou a relação entre psicopatologia, estressores cotidianos e qualidade de vida e o estado de atividade do LES em 129 pacientes, que foram divididas em dois grupos de acordo com a maior e menor atividade da doença.…”