Psychosocial Consequences of Wounds

Upton, Dominic; Upton, Penney

doi:10.1007/978-3-319-09653-7_1

Cited by 2 publications

(1 citation statement)

References 71 publications

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“…Where health-related quality of life involves a cognitive assessment an individual makes regarding the impact of their disease, wellbeing reflects their emotional response 4 . Wellbeing is more closely linked to mental health and is a state of being that enables a person to thrive 5 .…”

Section: Introductionmentioning

confidence: 99%

Depression is a more significant predictor for wellbeing in Inclusion Body Myositis than physical disability

Nunn,

Glenister,

Hird

et al. 2024

Preprint

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Objectives: (1) determine if there is a correlation between disability, depression, and wellbeing in people with IBM, (2) determine if disability and depression can predict wellbeing in people with IBM, and (3) identify the prevalence of depression and impaired wellbeing in participants with IBM. Methods: In this cross-sectional study, 101 participants with IBM completed the Neuromuscular Symptom Score (NSS), Personal Wellbeing Index (PWI), and Patient Health Questionnaire-9 (PHQ-9) surveys to serve as surrogate measures of physical disability, wellbeing, and depression respectively. Results: Linear regression identified that PHQ-9 significantly predicts PWI, however NSS does not, with a negative predictive value of depression for wellbeing (-2.7513, p < 0.001) and a positive predictive value of disability for wellbeing (0.0575, p = 0.764). Moderate to severe depression was reported in 78.2% of participants, and all but one participant reported reduced wellbeing. Conclusions: Depression is a more significant predictor of wellbeing than disability in participants diagnosed with IBM. There was a high prevalence of depression and reduced wellbeing in participants, highlighting the importance of assessing these factors to optimise treatment in IBM.

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Section: Introductionmentioning

confidence: 99%

Depression is a more significant predictor for wellbeing in Inclusion Body Myositis than physical disability

Nunn,

Glenister,

Hird

et al. 2024

Preprint

View full text Add to dashboard Cite

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Challenges and Opportunities of pH in Chronic Wounds

2019

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Regarded as a silent epidemic, chronic wounds are a global public health issue. Wound healing is a complex, synchronized cascade of physiological processes restoring the anatomic and functional integrity of the skin; however, chronic wounds fail to proceed through the wound healing cascade. Wound pH oscillates during wound healing, usually traversing from a neutral pH to an acidic pH, while chronic wounds perpetuate in an elevated alkaline milieu. Although a neglected clinical parameter, pH has implications for relatively all pathologies of wound healing affecting oxygen release, angiogenesis, protease activity, bacterial toxicity and antimicrobial activity. Despite the array of wound healing products currently marketed, understanding the implications of pH on arresting wound healing can stimulate innovation within this vast market.

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Psychosocial Consequences of Wounds

Cited by 2 publications

References 71 publications

Depression is a more significant predictor for wellbeing in Inclusion Body Myositis than physical disability

Depression is a more significant predictor for wellbeing in Inclusion Body Myositis than physical disability

Challenges and Opportunities of pH in Chronic Wounds

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