Psychosexual Symptoms and Treatment of Peyronie's Disease Within a Collaborative Care Model

Hartzell, Rose

doi:10.1002/sm2.45

Cited by 27 publications

(27 citation statements)

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“…12-14 Feelings of shame and embarrassment often accompany the physical symptoms of PD, with up to 81% of men reporting "emotional difficulties." 13 These feelings may persist or worsen with progression of the disease; depression has been reported in up to 48% of men.…”

Section: Prevalence and Significancementioning

confidence: 99%

Peyronie’s Disease: A Review of Etiology, Diagnosis, and Management

Bilgutay

Pastuszak

2015

Curr Sex Health Rep

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Peyronie’s Disease (PD) is a superficial fibrosing disorder of the penis resulting in plaque formation and penile deformity. Once considered rare, PD has more recently been found in up to 13% of men, and can negatively affect sexual and psychosocial function of both patients and their partners. While the etiology of PD is unclear, it is thought to result from an inciting traumatic event followed by aberrant fibrosis or dysregulated wound healing. The evaluation of men presenting with PD includes a detailed history and physical exam, focusing on the penis in both the flaccid and erect states. PD is often associated with erectile dysfunction (ED), as well as several other comorbidities. Laboratory testing is not needed to diagnose PD, although given the associations between PD and systemic diseases including hypogonadism, diabetes, and cardiovascular disease, screening and work-up for these conditions in men with PD may be warranted. Treatment modalities for PD are diverse and include oral, topical, intralesional, mechanical, and surgical therapies. Oral, topical, and mechanical therapies generally have little evidence supporting their efficacy. Several intralesional therapies, including interferon α2b and collagenase Clostridium hystiolyticum have demonstrated efficacy in the treatment of PD. Surgical treatment, indicated in men with significant, stable deformity, includes plication of the tunica albuginea, plaque incision/excision and grafting, and placement of inflatable penile prosthesis (IPP) with or without additional maneuvers to achieve desired results, and has high success rates.

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Section: Prevalence and Significancementioning

confidence: 99%

Peyronie’s Disease: A Review of Etiology, Diagnosis, and Management

Bilgutay

Pastuszak

2015

Curr Sex Health Rep

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“…An analysis of the psychosexual factors associated with PD included several elements of emotional distress in these patients. This included feelings of shame, inadequacy and reduced self‐worth, body image dysmorphia, isolation and avoidance of intimacy, fear of rejection, anger, and depression 3 . While clinically this psychosocial impact can be apparent, with regard to research this has not been studied extensively 4 .…”

Section: Introductionmentioning

confidence: 99%

Defining the impact of Peyronie's disease on the psychosocial status of gay men

et al. 2020

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Background Little sexual health research has been conducted in gay men. Anecdotally, this population seems to experience more bother related to Peyronie's disease (PD). Objectives To examine the impact of PD on psychosocial factors in gay vs straight men. Materials and Methods All PD patients who were seen in the sexual medicine clinic were included. They completed three instruments: the PD questionnaire (PDQ), Self‐Esteem and Relationship (SEAR) questionnaire, and a depression questionnaire (CES‐D). We described demographics and sexual variables by sexual orientation. We then compared PDQ items and summary scores by sexual orientation, using a series of independent samples t tests. Results 34 consecutive gay and 464 straight men were included. Age and baseline characteristics were similar between the two cohorts, with the exception that fewer gay men were partnered (56% vs 87%, P < .01), and those with a partner had a shorter relationship duration: 109 ± 9 months vs 262 ± 175 months, P < .01. For the SEAR questionnaire, gay men demonstrated a more significant psychosocial impact of PD overall with lower SEAR sums (41 vs 57, P = .01) and a lower sexual relationship subdomain score (28 vs 47, P < .01). 41% of gay men vs 26% of straight men had CES‐D scores consistent with depression as defined by a score of ≥16 (P = .09). In the PDQ domains, gay men scored less favorably with regard to bother scores (7 vs 5, P = .03) and pain scores (8 vs 4, P = .04). Discussion Gay men with PD experience significantly more psychosocial impact as evidenced by less favorable SEAR sum and sexual relationship scores, CES‐D scores, and PDQ pain and bother domain scores. Conclusion The psychosocial impact of PD is significant in all men, but it appears to be greater in gay men.

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“…13 Assessment of the emotional, psychosexual, and relationship aspects of the patient’s PD symptoms that negatively impact the patient’s quality of life, are needed to prioritize treatment goals. 14…”

Section: Introductionmentioning

confidence: 99%

Non-invasive treatment in the management of Peyronie’s disease

Randhawa

2019

Therapeutic Advances in Urology

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Peyronies disease (PD) is estimated to affect approximately 3–9% of men worldwide and maybe associated with pain, erectile dysfunction and penile deformity including shortening. The condition has significant debilitating effects on quality of life, self-esteem and psychological wellbeing in addition to sexual function. Surgical results add further to this by patients having dissatisfaction with various aspects of outcomes. Non-surgical management may allow patients to avoid the morbidities associated with surgery and still achieve improved functional and aesthetic outcomes. Several non-surgical options are currently being employed in the treatment of PD that may reduce or stabilize both objective measures (e.g. penile length and deformity) and subjective measures (including sexual function, pain and partner satisfaction). Nonsurgical management can allow patients to avoid the morbidities associated with surgery and still achieve improved functional and aesthetic outcomes. In this article we explore the current non-surgical management options for PD including oral, mechanical therapies, intralesional and topical treatments. We also briefly discuss future treatment options in the form of stem cell therapy.

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Psychosexual Symptoms and Treatment of Peyronie's Disease Within a Collaborative Care Model

Cited by 27 publications

References 56 publications

Peyronie’s Disease: A Review of Etiology, Diagnosis, and Management

Peyronie’s Disease: A Review of Etiology, Diagnosis, and Management

Defining the impact of Peyronie's disease on the psychosocial status of gay men

Non-invasive treatment in the management of Peyronie’s disease

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