Psychophysiological Aspects of Methamphetamine Abuse

Wray, Janet

doi:10.3109/10884600009041773

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…This excess amount of neurotransmitters in the synapses produces sensations of euphoria, lowered inhibitions, feelings of invincibility, increased wakefulness, heightened sexual experiences, and hyperactivity resulting from increased energy for extended periods of time[ 8 ]. Deleterious short-term effects include increased heart and respiration rates, hyperthermia, chest pain, hypertension, increased respiration, decreased appetite, anorexia, irritability, confusion, tremors, convulsions, anxiety, aggressiveness, and symptoms of psychosis such as hallucinations and paranoia[ 4 , 9 , 10 ]. This is followed by mental and physical exhaustion, headaches, irritability, reduced concentration, hunger, decreased energy, anhedonia, and a craving for more MA[ 3 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Risk factors for methamphetamine use in youth: a systematic review

et al. 2008

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BackgroundMethamphetamine (MA) is a potent stimulant that is readily available. Its effects are similar to cocaine, but the drug has a profile associated with increased acute and chronic toxicities. The objective of this systematic review was to identify and synthesize literature on risk factors that are associated with MA use among youth.More than 40 electronic databases, websites, and key journals/meeting abstracts were searched. We included studies that compared children and adolescents (≤ 18 years) who used MA to those who did not. One reviewer extracted the data and a second checked for completeness and accuracy. For discrete risk factors, odds ratios (OR) were calculated and when appropriate, a pooled OR with 95% confidence intervals (95% CI) was calculated. For continuous risk factors, mean difference and 95% CI were calculated and when appropriate, a weighted mean difference (WMD) and 95% CI was calculated. Results were presented separately by comparison group: low-risk (no previous drug abuse) and high-risk children (reported previous drug abuse or were recruited from a juvenile detention center).ResultsTwelve studies were included. Among low-risk youth, factors associated with MA use were: history of heroin/opiate use (OR = 29.3; 95% CI: 9.8–87.8), family history of drug use (OR = 4.7; 95% CI: 2.8–7.9), risky sexual behavior (OR = 2.79; 95% CI: 2.25, 3.46) and some psychiatric disorders. History of alcohol use and smoking were also significantly associated with MA use. Among high-risk youth, factors associated with MA use were: family history of crime (OR = 2.0; 95% CI: 1.2–3.3), family history of drug use (OR = 4.7; 95% CI: 2.8–7.9), family history of alcohol abuse (OR = 3.2; 95% CI: 1.8–5.6), and psychiatric treatment (OR = 6.8; 95% CI: 3.6–12.9). Female sex was also significantly associated with MA use.ConclusionAmong low-risk youth, a history of engaging in a variety of risky behaviors was significantly associated with MA use. A history of a psychiatric disorder was a risk factor for MA for both low- and high-risk youth. Family environment was also associated with MA use. Many of the included studies were cross-sectional making it difficult to assess causation. Future research should utilize prospective study designs so that temporal relationships between risk factors and MA use can be established.

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Section: Introductionmentioning

confidence: 99%

Risk factors for methamphetamine use in youth: a systematic review

et al. 2008

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“…As of yet, no research on apathy has been completed, but a study of cocaine use reveals that recently abstinent cocaine users have high levels of apathy, even after controlling for depressive symptoms (Kalechstein et al, 2002). Since the two drugs are similar (Wray, 2000), one should expect signs of apathy in methamphetamine users as well.…”

Section: Introductionmentioning

confidence: 99%

The impact of methamphetamine use on subjective well‐being in an Internet survey: preliminary findings

Looby¹,

Earleywine²

2007

Human Psychopharmacology

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Methamphetamine is one of the most widely used stimulants worldwide. Common reasons for use of the drug include efforts to improve or enhance one's life and to uplift one's mood. Nevertheless, acute effects of the drug lead to temporary improvements in mood followed by negative affect. The purpose of the present study was to expand on the current literature and examine other aspects of mood and satisfaction with life in methamphetamine users. Over 6000 adults completed an Internet survey and reported on depression, apathy, satisfaction with life, happiness, and subjective well-being, in addition to measures of methamphetamine use. We compared those who had used methamphetamine at least once within the past year (N = 610) to those who had never used (N = 6063). Methamphetamine use accounted for significant variance in depression, apathy, satisfaction with life, happiness, and subjective well-being even when alcohol and other drugs served as covariates. Methamphetamine use may decrease one's subjective well-being instead of enhancing it, which is contradictory to the perceptions of many users. Increasing awareness about methamphetamine's negative impact on mood and life satisfaction might help decrease prevalence of the drug's use and associated troubles.

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Psychophysiological Aspects of Methamphetamine Abuse

Cited by 2 publications

References 8 publications

Risk factors for methamphetamine use in youth: a systematic review

Risk factors for methamphetamine use in youth: a systematic review

The impact of methamphetamine use on subjective well‐being in an Internet survey: preliminary findings

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