Psychophysiological and Neurophysiological Aspects of Schizophrenia

Flekkøy, Kjell

doi:10.1111/j.1600-0447.1975.tb11090.x

Cited by 11 publications

(3 citation statements)

References 56 publications

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“…4 Additionally, among schizophrenia patients, different EEG characteristics can be seen, most notably the invariant alpha pattern where subjects exhibit well developed and unvarying alpha activity. 5 This pattern has been correlated with poor prognosis. On the other hand, some subjects exhibit poorly formed background activity.…”

Section: Eegs In Psychiatric Researchmentioning

confidence: 97%

Role of the Unquantified Electroencephalography in Psychiatric Research

Boutros¹,

Jacobson²,

Campbell³

1999

CNS spectr.

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This paper outlines potential research applications of the unquantified (paper or digital) electroencephalography (EEG) in psychiatry. Three main areas are highlighted: first, the need for thorough familiarity with the unquantified EEG is emphasized, including the ability to confidently recognize all normal and abnormal activities that could influence further analysis of the record as well as artifacts that can contaminate the tracings; second, the fact that definitive studies relating EEG abnormalities to psychiatric symptomatology and clinical response are lacking; and third, the potential for EEG to be utilized as a tool to decrease the risk of invasive research studies is discussed.

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Section: Eegs In Psychiatric Researchmentioning

confidence: 97%

Role of the Unquantified Electroencephalography in Psychiatric Research

Boutros¹,

Jacobson²,

Campbell³

1999

CNS spectr.

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“…It is difficult to relate the results of psychophysiological studies in schizophrenia to clinical data and to the results from biochemical, neuropathological and electroencephalographic investigations (Lang & Buss, 1965;Venables, 1975). This difficulty stems from a considerable lack of understanding of the biochemical and physiological basis of psychophysiological phenomena (Flekkoy, 1975). There are two opposing approaches to the understanding of the relationship between biochemical and psychophysiological events in schizophrenia: first, a global investigation of many variables whose aim is to produce correlations which can be used to generate theories of cause; secondly, a focused study on a single psychophysiological parameter whose physiological substrate is either known or is the subject of a powerful heuristic hypothesis.…”

Section: Introductionmentioning

confidence: 99%

Preliminary Communication Absence of cardiac deceleration in a signalled escape paradigm: a psychophysiological deficit in chronic schizophrenia

et al. 1978

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SynopsisFourteen chronic male schizophrenic patients and six male control subjects were com pared in an escape paradigm involving temporal warning of the presentation of an aversive tone stimulus to which an escape response was to be made. The characteristic heart rate deceleration shown immediately prior to the aversive stimulus by control subjects was absent in the schizophrenic group. Further features of this novel test paradigm distinguished the control and schizophrenic groups. This psychophysiological test procedure may be fruitful for schizophrenia research.

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“…A high spectral power of the beta frequencies has been found in schizophrenics and this EEG variable has been correlated to a state of 'cortical overload stimulation' (8,10,11,13,14,19). Significant differences between schizophrenics and controls have also been found in the delta, theta and alpha frequency bands (14,15,17).…”

Section: -23)mentioning

confidence: 99%

Computerized EEG in Schizophrenics

Kemali¹,

Vacca²,

Marcianò³

et al. 1980

Neuropsychobiology

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20 psychiatric patients without pharmacologic therapy and an homogeneous control group of 19 healthy subjects have been submitted to an electroencephalographic (EEG) investigation. Computerized spectral analyses of the main EEG frequency bands have been performed. The spectra have been determined by some geometrical descriptors: the relative activity, the barycentric frequency and the barycentric radius; also classic descriptors have been used as complementary ones. In the EEG profìle signifícant differences between patients and healthy subjects have been found. Some differences have also been observed among subgroups of schizophrenic patients. The geometrical descriptors applied in the EEG analysis are suggested as a useful method in the description of the basic characteristics of the main EEG frequency bands.

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Psychophysiological and Neurophysiological Aspects of Schizophrenia

Cited by 11 publications

References 56 publications

Role of the Unquantified Electroencephalography in Psychiatric Research

Role of the Unquantified Electroencephalography in Psychiatric Research

Preliminary Communication Absence of cardiac deceleration in a signalled escape paradigm: a psychophysiological deficit in chronic schizophrenia

Computerized EEG in Schizophrenics

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