Psychopathy, Mental Deficiency, Aggressiveness and the XYY Syndrome

Welch, John P.; Borgaonkar, D. S.; Herr, Helen M.

doi:10.1038/214500a0

Cited by 64 publications

(12 citation statements)

References 7 publications

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“…The (Case 1) patient had been convicted of rape at the age of 14 and therefore shows a similarity to the 20 cases of sexual crimes among XYY men described in the literature (16,18,21,37). Although he was of normal intelligence, he did not progress well in school (44), and the patient in Case 2 had no better than borderline intelligence similar to the retardates (6,7,19,33) and retarded criminals (5,7,12,23,41). Other similarities include the preoccupation with fire (11,21,23) and the normal anatomy and physiology except for tallness.…”

Section: Discussionsupporting

confidence: 58%

Two New Cases of XYY Chromosome Complement: And a Review of the Literature

Hoffman

1977

Canadian Psychiatric Association Journal

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Two cases with XYY chromosome complement are presented and compared with 153 cases described in the literature. Some patients with abnormalities of personality development and manifest psychopathology may have sex chromosome abnormalities and should be studied further for the interaction of genetic and environmental factors in personality development. In particular, tall, schizoid impulsive men with a history of criminality, arson or sexual offences should be screened for this particular genetic configuration. Because of the biased manner by which most of the cases are found, it is not yet known whether an XYY genotype results in a characteristic phenotype. What is needed is a genetic study of a normal population and a prospective study of newborns with various genotypes which would, unfortunately, create complex research and ethical problems.

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Section: Discussionsupporting

confidence: 58%

Two New Cases of XYY Chromosome Complement: And a Review of the Literature

Hoffman

1977

Canadian Psychiatric Association Journal

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“…An XYY sex chromosome complement, without any abnormal phenotypical effect, may be found in the general population (Forssman, Akesson, and Wallin, 1968). It may, on the other hand, be associated with the typical combination of tall stature and psychopathic behaviour (Price and Whatmore, 1967;Welch, Borgaonkar, and Herr, 1967). Alternatively, YY aneuploidy may be discovered because cytogenetical studies are prompted by the presence of a specific pathological condition, such as in the present case.…”

Section: Discussionmentioning

confidence: 57%

A case of XYY Down's syndrome confirmed by autoradiography.

Laxová¹,

McKeown²,

Saldaña³

et al. 1971

Journal of Medical Genetics

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“…Seven of the 12 patients in the present sample were clinically suspected of being XYY men before referral for karyotyping and five were not (see Table 1). These five were karyotyped as part of XYY chromosome surveys (Borgaonkar 1972, Cross et al 1969, Welch et al 1967.…”

Section: Xyy Syndromementioning

confidence: 99%

Cytogenetics, hormones and behavior disability: comparison of XYY and XXY syndromes

et al. 1974

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Two populations of phenotypic males, twelve 47,XYY and twelve 47,XXY patients, when compared for behavior disability, sexual practices, and social interaction, revealed that the XYY males had behavior disability involving a predominance of impulsive acting out and poor long term planning. By contrast, the XXY males manifested a deficiency or inhibition of action. With regard to sexual practices, the XYY males reported a greater frequency and diversity of sexual experience and imagery than did the XXY males, who appear to be sexually inert by comparison. For both XYY and XXY men, being alone took preference over group participation. The XXY men were more characterized by inertia and reclusiveness, while the XYY men were mobile and more likely to intrude on other people and their property.

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Psychopathy, Mental Deficiency, Aggressiveness and the XYY Syndrome

Cited by 64 publications

References 7 publications

Two New Cases of XYY Chromosome Complement: And a Review of the Literature

Two New Cases of XYY Chromosome Complement: And a Review of the Literature

A case of XYY Down's syndrome confirmed by autoradiography.

Cytogenetics, hormones and behavior disability: comparison of XYY and XXY syndromes

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