Psychopathology in Children of Inpatients With Depression: A Controlled Study

Welner, Zila; Welner, Amos; McCRARY, M Donald; Leonard, Mary Ann

doi:10.1097/00005053-197706000-00006

Cited by 117 publications

(21 citation statements)

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“…Knowledge of such differences is essential to further understanding of the specificity or breadth of risks for the development of psychopathology in children of depressed mothers, with implications for theory about risk as well as for pinpointing the targets of preventive interventions. Elevated rates not only of depression and other internalizing problems but also of conduct problems have been noted since the earliest studies on offspring of depressed mothers (e.g., Welner et al 1977). From a theoretical perspective, externalizing disorders in children with depressed mothers are interesting because they may reflect problems with dysregulated aggression (Radke-Yarrow et al 1992), a distinct pattern of inherited vulnerability perhaps related to behavioral disorders (e.g., alcoholism, substance abuse, or antisocial personality disorders) in first-degree relatives (Kovacs et al 1997;Williamson et al 1995), environmental risk such as the pattern of parenting that has been associated with conduct problems in general population samples, or particular interactions among genes, cognitive, affective, interpersonal, and other biological systems that lead to the emergence of externalizing rather than (or co-occurring with) internalizing disorders (Silberg and Rutter 2002).…”

Section: Maternal Depression and Multiple Aspects Of Youth Psychopathmentioning

confidence: 99%

Maternal Depression and Child Psychopathology: A Meta-Analytic Review

Goodman

Rouse

Connell

et al. 2011

Clin Child Fam Psychol Rev

2,176

158

1,761

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Although the association between maternal depression and adverse child outcomes is well established, the strength of the association, the breadth or specificity of the outcomes, and the role of moderators are not known. This information is essential to inform not only models of risk but also the design of preventive interventions by helping to identify subgroups at greater risk than others and to elucidate potential mechanisms as targets of interventions. A meta-analysis of 193 studies was conducted to examine the strength of the association between mothers' depression and children's behavioral problems or emotional functioning. Maternal depression was significantly related to higher levels of internalizing, externalizing, and general psychopathology and negative affect/behavior and to lower levels of positive affect/behavior, with all associations small in magnitude. These associations were significantly moderated by theoretically and methodologically relevant variables, with patterns of moderation found to vary somewhat with each child outcome. Results are interpreted in terms of implications for theoretical models that move beyond main effects models in order to more accurately identify which children of depressed mothers are more or less at risk for specific outcomes.

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Section: Maternal Depression and Multiple Aspects Of Youth Psychopathmentioning

confidence: 99%

Maternal Depression and Child Psychopathology: A Meta-Analytic Review

Goodman

Rouse

Connell

et al. 2011

Clin Child Fam Psychol Rev

2,176

158

1,761

View full text Add to dashboard Cite

show abstract

“…Differences are noted for suicidal risk in children of depressed parents when (a) suicidal risk is assessed as a broader continuum of thoughts or actions, (b) assessed across cumulative time points, or (c) large samples are available for study (e.g., Lewinsohn, Olino, & Klein, 2005;Weissman, Fendrich, Warner, & Wickramaratne, 1992;Welner, Welner, McCrary, & Leonard, 1977). Furthermore, when differences are noted, they primarily pertain to children of parents with MDD, for rarely have children of BD parents been a topic of inquiry.…”

mentioning

confidence: 99%

Suicidal risk in young adult offspring of mothers with bipolar or major depressive disorder: a longitudinal family risk study

Klimes‐Dougan¹,

Lee²,

Ronsaville³

et al. 2008

J Clin Psychol

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Recent evidence has highlighted suicidal risk associated with bipolar disorder (BD). Using a family risk approach, the goal of this study was to evaluate suicidal thoughts and behaviors longitudinally from childhood to young adulthood in children of mothers with BD, Major depressive disorder (MDD), and well mothers. Few group differences were found for cross-sectional assessments of suicidal thoughts and behavior in young adulthood; the offspring of MDD demonstrate an earlier onset and more persistent suicidality than other groups, but by young adulthood, BD offspring appear to be comparable to MDD offspring in their rates of suicidality. The longitudinal assessments reveal a pattern of higher suicidal risk in MDD offspring, more intermediate risk in BD offspring, and lower risk in well offspring. Precursors and correlates of suicidal thoughts and behaviors were also examined. These findings suggest diverse developmental trajectories based on family risk and have implications for planning preventive intervention.

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“…In addition, several investigators both of offspring of patients with affective disorders (McKnew, Cytryn, Efron, Gershon, & Bunney, 1979;Orvaschel, Weissman, & Kidd, 1980;Weissman et al, 1984;Welner, Welner, McCrary, & Leonard, 1977) and of offspring of patients with psychiatric disorders in general (Erlenmeyer-Kimling, Kestenbaum, Bird, & Hilldoff, 1984;Garmezy, 1984;Orvaschel, Weissman, Padian, & Lowe, 1981;Rutter, 1966) have noted that these children are not only at risk for any of a variety of behavior problems, but actually manifest such behavior problems to a greater extent than children of "normal" parents. In an attempt to determine the connection between parental psychopathology and children's behavior problems, Rutter (1966) concluded that, in general, the mechanism of "transmission" was not different for offspring of parents with mental illness and offspring of "normal" parents.…”

mentioning

confidence: 99%