Psychopathology and resilience following traumatic injury: A latent growth mixture model analysis.

deRoon‐Cassini, Terri; Mancini, Anthony D.; Rusch, Heather L.; Bonanno, George A.

doi:10.1037/a0018601

Cited by 324 publications

(294 citation statements)

References 47 publications

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“…17 Differing patterns of recovery, including a temporal decrease in general psychological distress as well as a stable trajectory characterised by minimal symptoms of distress over time, have also been identified among traumatic injury groups. 15,18 In combination, these findings suggest that psychological assessments administrated at various stages of the rehabilitation process are likely to yield different point prevalence estimates for probable anxiety.…”

Section: Introductionmentioning

confidence: 90%

Anxiety prevalence following spinal cord injury: a meta-analysis

Dorstyn

2016

Spinal Cord

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Study design: Meta-analysis. Objectives: Prevalence estimates indicate that anxiety following spinal cord injury (SCI) is a common problem. However, methodological differences between studies may impact the clinical interpretation of these data. Methods: Data from 18 independent studies (N participants = 3158), which reported the prevalence of an anxiety disorder or associated symptoms, were identified from the Embase, PubMed and PsycInfo databases. Proportions were the primary effect size estimate. Confidence intervals, fail-safe Ns and the I 2 statistic were additionally calculated to identify the extent to which findings were robust and consistent across studies. Results: Five per cent of participants met the criteria for either GAD or panic disorder, with Agoraphobia identified in 2.5%. These diagnostic data were, however, limited to two studies. Higher rates were noted for self-reported 'caseness' of anxiety, with 27% reporting clinically significant symptoms. Anxiety prevalence estimates varied across the individual self-report measures (range: 15-32%). Method of administration (range: 26-32%) did not impact significantly on these estimates nor did recruitment source, with similarly high anxiety levels reported by hospital (27%) and community (29%) samples. Conclusions: Early identification and treatment of anxiety are important in SCI rehabilitation, with a subgroup of individuals experiencing chronic symptoms. Further research is needed to establish guidelines for the interpretation of self-report data, including the use of clinical cutoffs.

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Section: Introductionmentioning

confidence: 90%

Anxiety prevalence following spinal cord injury: a meta-analysis

Dorstyn

2016

Spinal Cord

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“…a minimum score on a screening instrument). For example, three studies (Bryant et al, 2012; deRoon-Cassini et al, 2010; Jenewein et al, 2009) had a minimum hospital admission length (24–48 hours), and three studies (Bonne et al, 2001; Shalev et al, 2012; van Zuiden et al, 2017) had a minimum threshold or criterion for initial symptoms. These criteria screened for more severely injured or more symptomatic patients to be included in the studies.…”

Section: Resultsmentioning

confidence: 99%

“…However, participating studies sampled different communities (e.g. communities with differing rates of violent crimes; deRoon-Cassini et al, 2010; Schnyder, Wittmann, Friedrich-Perez, Hepp, & Moergeli, 2008) and applied study-specific inclusion/exclusion criteria (e.g. initial PTSD symptom severity, injury severity, and present and past mental disorders history) (Appendix 1).…”

Section: Discussionmentioning

confidence: 99%

“…For example, the JTOPS study (Shalev et al, 2012) had MVAs, work accidents, physical assaults, terrorist attacks, and other traumas as trauma categories, while the Midwest resilience study (deRoon-Cassini et al, 2010) had MVA, assaults, gunshot wounds, stabbings, falls, work accidents, household accidents, snowmobile accidents, and object-fell-on-person accidents. Based on epidemiological studies showing a higher conditional prevalence of PTSD following interpersonal trauma (Benjet et al, 2016), and categorization of the World Mental Health Survey (Karam et al, 2014), we recoded these variable into (1) MVAs, (2) other non-interpersonal trauma (e.g.…”

Section: Methodsmentioning

confidence: 99%

“…The International Consortium to Predict PTSD (ICPP) is an effort sponsored by the US National Institute of Mental Health to create a consortium of principal investigators of published and unpublished longitudinal PTSD studies (Bonne et al, 2001; Bryant, Creamer, O’Donnell, Silove, & McFarlane, 2008; deRoon-Cassini, Mancini, Rusch, & Bonanno, 2010; Hepp et al, 2008; Irish et al, 2008; Jenewein, Wittmann, Moergeli, Creutzig, & Schnyder, 2009; Matsuoka et al, 2009a; Mouthaan et al, 2014; Shalev et al, 2012, 2000, 2008; van Zuiden et al, 2017), combine their individual- and item-level data towards carrying out a pooled secondary analysis, and synthesize information about the predictors of PTSD. The ICPP’s goal is to pool and harmonize extant data sets so as to inform PTSD pathogenesis and prediction across trauma types, severity, geography, and clinical circumstances.…”

Section: Introductionmentioning

confidence: 99%

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Application of data pooling to longitudinal studies of early post-traumatic stress disorder (PTSD): the International Consortium to Predict PTSD (ICPP) project

Ratanatharathorn

Gevonden

et al. 2018

European Journal of Psychotraumatology

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Background: Understanding the development of post-traumatic stress disorder (PTSD) is a precondition for efficient risk assessment and prevention planning. Studies to date have been site and sample specific. Towards developing generalizable models of PTSD development and prediction, the International Consortium to Predict PTSD (ICPP) compiled data from 13 longitudinal, acute-care based PTSD studies performed in six different countries.Objective: The objectives of this study were to describe the ICPP’s approach to data pooling and harmonization, and present cross-study descriptive results informing the longitudinal course of PTSD after acute trauma.Methods: Item-level data from 13 longitudinal studies of adult civilian trauma survivors were collected. Constructs (e.g. PTSD, depression), measures (questions or scales), and time variables (days from trauma) were identified and harmonized, and those with inconsistent coding (e.g. education, lifetime trauma exposure) were recoded. Administered in 11 studies, the Clinician Administered PTSD Scale (CAPS) emerged as the main measure of PTSD diagnosis and severity.Results: The pooled data set included 6254 subjects (39.9% female). Studies’ average retention rate was 87.0% (range 49.1–93.5%). Participants’ baseline assessments took place within 2 months of trauma exposure. Follow-up durations ranged from 188 to 1110 days. Reflecting studies’ inclusion criteria, the prevalence of baseline PTSD differed significantly between studies (range 3.1–61.6%), and similar differences were observed in subsequent assessments (4.3–38.2% and 3.8–27.0% for second and third assessments, respectively).Conclusion: Pooling data from independently collected studies requires careful curation of individual data sets for extracting and optimizing informative commonalities. However, it is an important step towards developing robust and generalizable prediction models for PTSD and can exceed findings of single studies. The large differences in prevalence of PTSD longitudinally cautions against using any individual study to infer trauma outcome. The multiplicity of instruments used in individual studies emphasizes the need for common data elements in future studies.

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Recovery After Mild Traumatic Brain Injury in Patients Presenting to US Level I Trauma Centers

Nelson¹,

Temkin²,

Dikmen³

et al. 2019

JAMA Neurol

288

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IMPORTANCE Most traumatic brain injuries (TBIs) are classified as mild (mTBI) based on admission Glasgow Coma Scale (GCS) scores of 13 to 15. The prevalence of persistent functional limitations for these patients is unclear. OBJECTIVES To characterize the natural history of recovery of daily function following mTBI vs peripheral orthopedic traumatic injury in the first 12 months postinjury using data from the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) study, and, using clinical computed tomographic (CT) scans, examine whether the presence (CT+) or absence (CT−) of acute intracranial findings in the mTBI group was associated with outcomes. DESIGN, SETTING, AND PARTICIPANTS TRACK-TBI, a cohort study of patients with mTBI presenting to US level I trauma centers, enrolled patients from February 26, 2014, to August 8, 2018, and followed up for 12 months. A total of 1453 patients at 11 level I trauma center emergency departments or inpatient units met inclusion criteria (ie, mTBI [n = 1154] or peripheral orthopedic traumatic injury [n = 299]) and were enrolled within 24 hours of injury; mTBI participants had admission GCS scores of 13 to 15 and clinical head CT scans. Patients with peripheral orthopedic trauma injury served as the control (OTC) group. EXPOSURES Participants with mTBI or OTC. MAIN OUTCOMES AND MEASURES The Glasgow Outcome Scale Extended (GOSE) scale score, reflecting injury-related functional limitations across broad life domains at 2 weeks and 3, 6, and 12 months postinjury was the primary outcome. The possible score range of the GOSE score is 1 (dead) to 8 (upper good recovery), with a score less than 8 indicating some degree of functional impairment. RESULTS Of the 1453 participants, 953 (65.6%) were men; mean (SD) age was 40.9 (17.1) years in the mTBI group and 40.9 (15.4) years in the OTC group. Most participants (mTBI, 87%; OTC, 93%) reported functional limitations (GOSE <8) at 2 weeks postinjury. At 12 months, the percentage of mTBI participants reporting functional limitations was 53% (95% CI, 49%-56%) vs 38% (95% CI, 30%-45%) for OTCs. A higher percentage of CT+ patients reported impairment (61%) compared with the mTBI CT− group (49%; relative risk [RR], 1.24; 95% CI, 1.08-1.43) and a higher percentage in the mTBI CT−group compared with the OTC group (RR, 1.28; 95% CI, 1.02-1.60). CONCLUSIONS AND RELEVANCE Most patients with mTBI presenting to US level I trauma centers report persistent, injury-related life difficulties at 1 year postinjury, suggesting the need for more systematic follow-up of patients with mTBI to provide treatments and reduce the risk of chronic problems after mTBI.

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Psychopathology and resilience following traumatic injury: A latent growth mixture model analysis.

Cited by 324 publications

References 47 publications

Anxiety prevalence following spinal cord injury: a meta-analysis

Anxiety prevalence following spinal cord injury: a meta-analysis

Application of data pooling to longitudinal studies of early post-traumatic stress disorder (PTSD): the International Consortium to Predict PTSD (ICPP) project

Recovery After Mild Traumatic Brain Injury in Patients Presenting to US Level I Trauma Centers

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