Psychopathological Variables and Sleep Quality in Psoriatic Patients

Abstract

Psoriasis is an inflammatory disease frequently associated with psychiatric disturbances and sleep disorders. The aim of the study was to assess the prevalence of depression, interaction anxiety, audience anxiety, and sleep quality in psoriatic patients. One hundred and two psoriatic patients were enrolled and underwent the following questionnaires: Zung Self-Rating Depression Scale (SDS), Interaction Anxiousness Scale (IAS), Audience Anxiousness Scale (AAS), Pittsburgh Sleep Quality Index (PSQI). The severity of skin lesions was assessed by Psoriasis Area Severity Index (PASI). The presence of a link between clinical variables and with demographic data has been investigated. Psoriasis was linked to depression, interaction and audience anxiety, as well as to poor sleep quality; 37.5% of patients were depressed, 46.1% scored above 37 at the IAS, 47.1% scored above 33 at the AAS. Thirty-nine subjects (38.2%) presented a PSQI ≥ 5. An association between interaction anxiety and lower limbs psoriasis-related erythema as well as between PSQI and head psoriasis-related erythema was found, particularly among male patients. Hence, psoriatic patients should be assessed from a holistic point of view, in order to identify associated disorders that could benefit from targeted treatments.

Relationship between rosacea and sleep

“…Sleep quality has been investigated in skin diseases such as psoriasis and atopic dermatitis 42–44 . A percentage of 38.2–60% of psoriatic patients presented poor sleep quality (PSQI, >5) 42,45–48 . The mean PSQI score varies 6.5–8.1 in psoriatic patients, 42,46,49 Three of the seven PSQI components, namely subjective sleep quality, habitual sleep efficiency and daytime dysfunction, were significantly elevated in psoriasis 46 .…”

Sleep quality among adult patients with chronic dermatoses

“…Sleep disturbance seems to be a common Psrelated problem in affected patients [18]. Eight reviewed studies were based on the PSQI questionnaire [44,[48][49][50][51][52][53][54], with six of them being case-control investigations [44, 48-50, 53, 54]. The mean PSQI scores ranged from 4.4 to 9.2 points ( Figure 1) [44,48,49,[51][52][53], and were significantly higher compared to controls (p < 0.01) ( Table 2) [44,48,53,54].…”

“…In contrast to studies listed above, Stinco et al [49] did not observe a link between psoriasis and poor sleep quality. In published data among Ps patients, a significant influence on subjective sleep quality [50,53], daytime Yano et al [41] Bender et al [42] Kaaz et al [44] Kaaz et al [44] Shutty et al [48] Stinco et al [49] Luca et al [51] Henry et al…”

Patient perceptions of clear/almost clear skin in moderate‐to‐severe plaque psoriasis: results of the Clear About Psoriasis worldwide survey

“…In addition to the effects of skin lesions on appearance, symptoms such as pain and itch are bothersome and interfere with daily activities. 4,5 Psoriasis patients are at substantially increased risk of depression, anxiety and suicidality. 3 Psoriasis and its associated stigmatization exert harmful effects on multiple dimensions of health-related quality of life (QoL), including relationships, work productivity, ability to sleep and mental health.…”

“…3 Psoriasis and its associated stigmatization exert harmful effects on multiple dimensions of health-related quality of life (QoL), including relationships, work productivity, ability to sleep and mental health. 4,5 Psoriasis patients are at substantially increased risk of depression, anxiety and suicidality. 6,7 Depression contributes to the increased mortality in psoriasis patients, which underscores its devastating psychosocial impact.…”