“…Regarding psychopathology in NS, internalizing and externalizing behavioural problems have been frequently reported by parents of children with NS (Alfieri et al, 2014;Garg et al, 2017;Pierpont, Tworog-Dube, & Roberts, 2015;Sarimski, 2000;Van der Burgt et al, 1999;Wood, Massarano, Super, & Harrington, 1995). Although anxiety and mood problems have been described rather frequently (Noonan, 2005;Smpokou, Tworog-Dube, Kucherlapati, & Roberts, 2012;Wingbermühle et al, 2012a;Pierpont et al, 2015;Perrino et al, 2018) and the prevalence of symptoms of Attention Deficit-Hyperactivity Disorder and Autism Spectrum Disorder seems to be higher in children and adolescents with NS than in the general population (Adviento et al, 2014;Alfieri et al, 2014;Garg et al, 2017;Perrino et al, 2018;Pierpont et al, 2015;Smpokou et al, 2012), only few systematic studies regarding psychopathology in adults with NS are yet available. In a previous study of our research group, significantly higher levels of self-reported distress in social situations-but equal levels of social avoidant behaviour-were found in adults with NS in comparison with controls, as well as higher levels of anger-hostility and obsessive-compulsive complaints, mostly reflecting subjective cognitive difficulties (Wingbermühle et al, 2012a).…”