Psychomotor Tremor and Proprioceptive Control Problems in Current and Former Stimulant Drug Users: An Accelerometer Study of Heavy Users of Amphetamine, MDMA, and Other Recreational Stimulants

Downey, Luke A.; Tysse, Brenda; Ford, Talitha C.; Samuels, Angela C.; Wilson, Rory P.; Parrott, Andrew C.

doi:10.1002/jcph.925

Cited by 14 publications

(8 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Identifying and quantifying how internal state may drive behaviour is non-trivial and can often only be indirectly inferred . Some aspects of animals' internal state have been investigated using accelerometers which are sensitive to micro-movements and postures indicative of chemical, disease and affective states (Downey et al, 2017;Wilson et al, 2014), including vigilance behaviour, a stress-related response (Kröschel, Reineking, Werwie, Wildi, & Storch, 2017). Alongside accelerometers, other key sensors that can provide insights into internal state include heart rate, internal temperature and neurological sensors (Rattenborg et al, 2016).…”

Section: Why Is the Animal Moving?mentioning

confidence: 99%

Optimizing the use of biologgers for movement ecology research

Williams

Taylor

Benhamou

et al. 2019

Journal of Animal Ecology

Self Cite

225

233

View full text Add to dashboard Cite

1. The paradigm-changing opportunities of biologging sensors for ecological research, especially movement ecology, are vast, but the crucial questions of how best to match the most appropriate sensors and sensor combinations to specific biological questions and how to analyse complex biologging data, are mostly ignored.2. Here, we fill this gap by reviewing how to optimize the use of biologging techniques to answer questions in movement ecology and synthesize this into an Integrated Biologging Framework (IBF).3. We highlight that multisensor approaches are a new frontier in biologging, while identifying current limitations and avenues for future development in sensor technology.4. We focus on the importance of efficient data exploration, and more advanced multidimensional visualization methods, combined with appropriate archiving and sharing approaches, to tackle the big data issues presented by biologging. We also discuss the challenges and opportunities in matching the peculiarities of specific sensor data to the statistical models used, highlighting at the same time the large advances which will be required in the latter to properly analyse biologging data.

show abstract

Section: Why Is the Animal Moving?mentioning

confidence: 99%

Optimizing the use of biologgers for movement ecology research

Williams

Taylor

Benhamou

et al. 2019

Journal of Animal Ecology

Self Cite

225

233

View full text Add to dashboard Cite

show abstract

“…CNS depressants will generally lengthen reaction times but may increase errors through reduced alertness and vigilance/attention. When combined with drug-induced feelings of confidence, these changes can make any psychoactive drug dangerous for practical skills such as car driving [ 4 , 55 , 100 ]. Their chronic use can also be damaging.…”

Section: Neurocognitive Deficitsmentioning

confidence: 99%

Mood Fluctuation and Psychobiological Instability: The Same Core Functions Are Disrupted by Novel Psychoactive Substances and Established Recreational Drugs

Parrott

2018

Brain Sciences

View full text Add to dashboard Cite

Many novel psychoactive substances (NPS) have entered the recreational drug scene in recent years, yet the problems they cause are similar to those found with established drugs. This article will debate the psychobiological effects of these newer and more traditional substances. It will show how they disrupt the same core psychobiological functions, so damaging well-being in similar ways. Every psychoactive drug causes mood states to fluctuate. Users feel better on-drug, then feel worse off-drug. The strength of these mood fluctuations is closely related to their addiction potential. Cyclical changes can occur with many other core psychobiological functions, such as information processing and psychomotor speed. Hence the list of drug-related impairments can include: homeostatic imbalance, HPA axis disruption, increased stress, altered sleep patterns, neurohormonal changes, modified brain rhythms, neurocognitive impairments, and greater psychiatric vulnerability. Similar patterns of deficit are found with older drugs such as cocaine, nicotine and cannabis, and newer substances such as 3,4-methylenedioxymethamphetamine (MDMA), mephedrone and spice. All psychoactive drugs damage human well-being through similar basic neuropsychobiological mechanisms.

show abstract

“…Some patterns of bingeing were quite extreme, with repeated MDMA self-dosing for 48 hours or more without sleep (Topp et al, 1999). Some very experienced users inject MDMA (Topp et al, 1999;Downey et al (2017)), although the hit can be 'too intense to enjoy' and the post-drug comedown even worse than usual.…”

Section: Causes Of Death: Medical Treatments and Prevention Strategiesmentioning

confidence: 99%