Psychometric validation of the O’leary-Sant interstitial cystitis symptom index in a clinical trial of pentosan polysulfate sodium

Lubeck, Deborah P.; Whitmore, Kristene; Sant, Grannum R.; Alvarez-Horine, Sarah; Lai, Chinglin

doi:10.1016/s0090-4295(01)01126-8

Cited by 125 publications

(75 citation statements)

References 3 publications

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“…Worst symptoms were described as a median pain of 9 and urgency of 8; 119 (86%) had urinary frequency of ≥11/24 hours; and 98 (71%) described ≥3/night nocturia. O'Leary-Sant scores (12) were very similar to those in a recent large clinical trial of IC/PBS (13) . Hunner's ulcers were found in 6/100 cystoscopies (6%).…”

Section: Resultssupporting

confidence: 72%

Using the International Continence Society’s definition of painful bladder syndrome

Warren

Meyer

Greenberg

et al. 2006

Urology

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Objectives-The case definition of interstitial cystitis (IC) is in flux. The International Continence Society (ICS) suggested a definition for the painful bladder syndrome (PBS), a concept embraced by many IC investigators, some of whom have used the name IC/PBS. In a study of recent onset IC/ PBS patients, we had two objectives: to determine 1) what proportion met the ICS definition and 2) how did those who met the definition differ from those who did not.Methods-Having recruited women who had recent onset IC/PBS for an ongoing case control study to identify its risk factors, we studied our first 138 eligible cases to identify those who met the ICS definition. We then compared those who met the definition to those who did not by variables acquired through interviews and medical records. The most liberal interpretation of the ICS definition did not include 47/138 (34%) of our cases. Comparing these to the 91 (66%) who did meet the ICS criteria, we found that 96/97 clinical variables, including many generally thought characteristic of IC/PBS, were not significantly different between the 2 groups. Results-The

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Section: Resultssupporting

confidence: 72%

Using the International Continence Society’s definition of painful bladder syndrome

Warren

Meyer

Greenberg

et al. 2006

Urology

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“…The OLS is auseful questionnaire made for IC patients to objectively evaluate the severity of symptoms, diagnosis, and effects of treating responsiveness and is used throughout the world [14]. Among the 41 IC patients, only 34 patients properly completed the OLS questionnaire.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Voiding Questionnaires Between Female Interstitial Cystitis and Female Idiopathic Overactive Bladder

Kim

2010

Int Neurourol J

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Purpose: This study aimed to find out any different characteristics in various different voiding symptom questionnaires in the outpatient clinics between interstitial cystitis and overactive bladder. Materials and Methods: Between October 2005 and December 2007, retrospectively were analyzed the consecutive 41 IC female patients' and 43 OAB female patients' questionnaires, who had completed three questionnaires at the outpatient department (Incontinence Quality of Life; I-QoL, King's Health Questionnaire; KHQ, International Prostate Symptom Score; IPSS). Additionally, the 41 IC patients also completed O'Leary Sant Questionnaire (OLS, or ICSI/ICPI). Results: No statistical differences existed in age and symptom duration between two groups (p>0.05). In I-QoL, only the social embarrassment score was statistically different between two groups (p<0.05), but the total score, avoidance and limiting behavior, and psychosocial impact scores were not (p>0.05). In KHQ, the general health perceptions, impact on life, social limitations, personal relationships, emotions, and sleep/energy scores were statistically different (p<0.033), but the role limitations, physical limitations, and incontinence severity measures scores were not (p>0.059). In IPSS, the straining symptom, and quality of life scores were different between two groups (p<0.05). The IC patients also completed OLS questionnaire with mean interstital cystitis symptom index score of 14.10±3.92, and interstitial cystitis problem index score of 11.79±3.75. Conclusions: This study showed that some differences among symptom questions in questionnaires did exist between the two groups and that the IC group had much more impaired quality of life than the OABs.

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“…5 The process began with a 23-item index, and analysis suggested a 4-item symptom and problem index focusing on urgency, frequency, nocturia and pain over the past month, met standards for variability, test retest reliability, internal consistency and construct validity. 5 Lubeck and colleagues 11 assessed the utility of the ICSI in 376 patients with IC enrolled in a trial of varying doses of pentosan polysulfate sodium. They also found the ICSI to be a valid, reliable and responsive measure of change in IC symptoms.…”

Section: Symptom Scores (Recommended)mentioning

confidence: 99%

“…They also found the ICSI to be a valid, reliable and responsive measure of change in IC symptoms. 11 As with the UW-IC Scale, Propert and coauthors 10 demonstrated that the ICSI and ICPI were both responsive to change in patients with IC. An interesting finding by Diggs and colleagues 12 was that the ICSI underestimated the degree of urgency in IC patients compared with questioning following the International Continence Society definition.…”

Section: Symptom Scores (Recommended)mentioning

confidence: 99%

Diagnosis of interstitial cystitis

Carr

Corcos

Nickel

et al. 2013

CUAJ

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Psychometric validation of the O’leary-Sant interstitial cystitis symptom index in a clinical trial of pentosan polysulfate sodium

Cited by 125 publications

References 3 publications

Using the International Continence Society’s definition of painful bladder syndrome

Using the International Continence Society’s definition of painful bladder syndrome

Comparison of Voiding Questionnaires Between Female Interstitial Cystitis and Female Idiopathic Overactive Bladder

Diagnosis of interstitial cystitis

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