Abstract:To date, 7 of the HRPs developed an affective disorder. These findings suggest that a REM sleep dysregnlation not overt under basal conditions may be demasked by cRIT. In an ongoing study we examine REM sleep dysregnlation with the cRIT in healthy subjects with respect to the HLA-DR2-system and other biological indicators related to affective disorders, i.e. responsitivity of the HPA axis, and the psychometric profile of the subjects.
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