Psychological symptoms in Chinese nurses may be associated with predisposition to chronic disease: a cross-sectional study of suboptimal health status

Abstract

Background Suboptimal health status (SHS) is a reversible state between ideal health and illness and it can be effectively reversed by risk prediction, disease prevention, and personalized medicine under the global background of predictive, preventive, and personalized medicine (PPPM) concepts. More and more Chinese nurses have been troubled by psychological symptoms (PS). The correlation between PS and SHS is unclear in nurses. The purpose of current study is to investigate the prevalence of SHS and PS in Chinese nurses and the relationship between SHS and PS along with predisposing factors as well as to discuss the feasibility of improving health status and preventing diseases according to PPPM concepts in Chinese nurses. Methods A cross-sectional study was conducted with the cluster sampling method among 9793 registered nurses in Foshan city, China. SHS was evaluated with the Suboptimal Health Status Questionnaire-25 (SHSQ-25). Meanwhile, the PS of depression and anxiety were evaluated with Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS) self-assessment questionnaires. The relationship between PS and SHS in Chinese nurses was subsequently analyzed. Results Among the 9793 participants, 6107 nurses were included in the final analysis. The prevalence of SHS in the participants was 74.21% (4532/6107) while the symptoms of depression and anxiety were 47.62% (2908/6107) and 24.59% (1502/6107) respectively. The prevalence of SHS in the participants with depression and anxiety was significantly higher than those without the symptoms of depression (83.3% vs 16.7%, P < 0.001) and anxiety (94.2% vs 5.8%, P < 0.0001). The ratio of exercise habit was significantly lower than that of non-exercise habit (68.8% vs 78.4%, P < 0.001) in SHS group. Conclusions There is a high prevalence of SHS and PS in Chinese nurses. PS in Chinese nurses are associated with SHS. Physical exercise is a protective factor for SHS and PS so that the exercise should be strongly recommended as a valuable preventive measure well in the agreement with PPPM philosophy. Along with SDS and SAS, SHSQ-25 should also be highly recommended and applied as a novel predictive/preventive tool for the health measures from the perspectives of PPPM in view of susceptible population and individual screening, the predisposition to chronic disease preventing, personalization of intervention, and the ideal health state restoring.

Prevalence of stress, depression, anxiety and sleep disturbance among nurses during the COVID-19 pandemic: A systematic review and meta-analysis

“…The overall pooled point estimates of depression reported by the 62 studies [ 19 , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , 34 , 35 , 37 , 39 , 42 , 43 , 45 , 48 , 49 , 51 , [53] , [54] , [55] , [56] , [57] , 62 , [64] , [65] , [66] , [67] , [71] , [72] , [73] , [74] , [77] , [78] , [79] , [80] , [81] , [82] , [83] , [84] , [85] , [86] , [87] , [88] , 90 , 91 , [94] , [95] , [96] , [99] , [100] , [101] , [102] , [103] , [105] , [106] , [107] , [108] ] varied between 9% and 89% ( Fig. 4 : forest plots).…”

Mitochondriopathies as a Clue to Systemic Disorders—Analytical Tools and Mitigating Measures in Context of Predictive, Preventive, and Personalized (3P) Medicine

“…However, a variety of conditions causing excessive ROS production, such as exposure to genotoxic environments, multi-factorial stress, suboptimal health conditions, and metabolic syndromes [ 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 ], may lead to unrepaired mitochondrial DNA (mtDNA) damage and concomitant functional defects in mitochondrial complexes I and III, associated with significantly increased uncontrolled formation of extremely aggressive ·O2- [ 3 ]. The arising imbalanced overproduction of ROS and consequent oxidative damage to mitochondrial structures impairs the ability of mitochondria to synthesize an appropriate amount of ATP [ 18 ] and, therefore, significantly reduces the energy resources of the cell needed to perform all the vital functions including highly energy-consuming DNA repair [ 35 ].…”

“…Corresponding analytical tools Application of specialized surveys [ 26 , 29 , 30 ] Broad application and comprehensive analysis of liquid biopsy [ 7 , 9 , 10 ] Individualized patient profiling and innovative screening programs focused on young populations [ 11 , 12 , 167 ] Risk assessment, predictive, and companion diagnostics [ 10 ] Multi-omics, multi-parametric analysis, and machine learning [ 171 , 172 , 173 ] …”

Associated Factors of Suboptimal Health Status Among Adolescents in China: A Cross-Sectional Study

“… 4 , 11 , 20 , 27 Similarly, 74.21% prevalence rate found among nurses in China. 26 The prevalence rate of SHS found 65%.02 in youths, 71.08% in middle-aged adults and 72.48% in older adults. Additionally, SHS was found statistically significant among different profession, such as blue-collar workers had higher (73.71%) compared to white-collar workers, and SHS decreased with increased educational level.…”

“…The prevalence of SHS is varied among different age groups, gender, geographic region, and occupations. 20 , 25 , 26 It has found 51.2% in college students, whereas, 69.46% 21 in adults and that seems to be increasing with age 21 and high prevalence noted in rural area compared to urban settings. 4 Likewise, the prevalence of SHS had seen higher in women compared to men, which looks the same status from children to adult population.…”