Psychological outcome of ECMO‐eligible neonates with severe respiratory failure treated using conventional medical therapy

Mathias, Jane L.; Clark, S. M.; Nettelbeck, T.; James, Stanley L.; Da, White

doi:10.1111/j.1440-1754.1995.tb00854.x

J Paediatrics Child Health

1995

DOI: 10.1111/j.1440-1754.1995.tb00854.x

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Psychological outcome of ECMO‐eligible neonates with severe respiratory failure treated using conventional medical therapy

Jane L. Mathias

S. M. Clark

T. Nettelbeck

et al.

Abstract: Improvements to conventional treatments indicate that ECMO eligibility criteria may need to be revised to identify accurately those infants who are at extreme risk of mortality if treated conventionally.

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1999

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Cited by 2 publications

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“…Developmental follow-up studies on these children have indicated survival rates of about 80% and 10 to 20% rates of long-term neurodevelopmental sequelae (Wildin et al 1994, Geven et al 1995, Mathias et al 1995. The largest outcome study to date (Glass et al 1995), with a total of 103 children seen at age 5 years, found a survival rate of 83% at discharge.…”

mentioning

confidence: 99%

Survivors of neonatal extracorporeal membrane oxygenation at school age: unusual findings on intelligence testing

Iklé¹,

Iklé²,

Moreland

et al. 1999

Develop Med Child Neuro

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Data are presented on 17 children who received extracorporeal membrane oxygenation (ECMO) in the neonatal period for persistent pulmonary hypertension (PPHN). These children are being followed as part of a larger program of follow-up research on children who have been treated for PPHN with several treatment methods. On intelligence testing at ages 5 to 8 years, these 17 children had unusual patterns of results. A higher-than-predicted percentage of the ECMO survivors had discrepancies between their Verbal and Performance IQ and a muchhigher-than-predicted percentage had areas of unusual strength or weakness on their IQ subtest scores. Also, there was a significant correlation between the amount of time a child received ECMO and the child's Performance IQ: the longer the child received ECMO, the higher the Performance IQ. While findings of unusual weaknesses or deficits on intelligence testing at school age in children who have been severely ill in the neonatal period are not unusual, findings of high scores and areas of strength are not easily explained, particularly when these findings seem to relate to an invasive treatment like ECMO. Similar findings have been reported in two other small studies, which suggest that the impact of ECMO on the developing infant brain may not be purely detrimental.

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mentioning

confidence: 99%

Survivors of neonatal extracorporeal membrane oxygenation at school age: unusual findings on intelligence testing

Iklé¹,

Iklé²,

Moreland

et al. 1999

Develop Med Child Neuro

View full text Add to dashboard Cite

show abstract

Survivors of neonatal extracorporeal membrane oxygenation at school age: unusual findings on intelligence testing

Iklé

Moreland

et al. 1999

Dev Med Child Neurol

View full text Add to dashboard Cite

Data are presented on 17 children who received extracorporeal membrane oxygenation (ECMO) in the neonatal period for persistent pulmonary hypertension (PPHN). These children are being followed as part of a larger program of follow-up research on children who have been treated for PPHN with several treatment methods. On intelligence testing at ages 5 to 8 years, these 17 children had unusual patterns of results. A higher-than-predicted percentage of the ECMO survivors had discrepancies between their Verbal and Performance IQ and a much-higher-than-predicted percentage had areas of unusual strength or weakness on their IQ subtest scores. Also, there was a significant correlation between the amount of time a child received ECMO and the child's Performance IQ: the longer the child received ECMO, the higher the Performance IQ. While findings of unusual weaknesses or deficits on intelligence testing at school age in children who have been severely ill in the neonatal period are not unusual, findings of high scores and areas of strength are not easily explained, particularly when these findings seem to relate to an invasive treatment like ECMO. Similar findings have been reported in two other small studies, which suggest that the impact of ECMO on the developing infant brain may not be purely detrimental.

show abstract

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Psychological outcome of ECMO‐eligible neonates with severe respiratory failure treated using conventional medical therapy

Abstract: Improvements to conventional treatments indicate that ECMO eligibility criteria may need to be revised to identify accurately those infants who are at extreme risk of mortality if treated conventionally.

Cited by 2 publications

References 22 publications

Survivors of neonatal extracorporeal membrane oxygenation at school age: unusual findings on intelligence testing

Survivors of neonatal extracorporeal membrane oxygenation at school age: unusual findings on intelligence testing

Survivors of neonatal extracorporeal membrane oxygenation at school age: unusual findings on intelligence testing

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