Psychological Mechanisms of Internalized HIV Stigma Affect Sleep Impairment among People Living with HIV in China: A follow-up Study

Yuan, Guangzhe Frank; Qiao, Shan; Li, Xiaoming; Zhou, Yuejiao; Shen, Zhiyong

doi:10.1007/s10461-023-04236-4

Cited by 4 publications

(1 citation statement)

References 92 publications

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“…Regarding integrase inhibitor-based ART has fewer reported sleep-related side effects 31 compared to efavirenz 32 , which is known to increase sleep disturbances, this finding may reflect the increased use of integrase inhibitors-based ART instead of efavirenz. In addition, considering previous findings suggesting an association between stigma and sleep impairment 33 , it is plausible that the decreasing HIV-related stigma over time 34 may have influenced the lower prevalence of sleep disturbance observed from 2015 onward.…”

Section: Discussionmentioning

confidence: 96%

The prevalence and moderating factors of sleep disturbances in people living with HIV: a systematic review and meta-analysis

Lee,

Oh,

Park

et al. 2024

Sci Rep

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This systematic review and meta-analysis aimed to investigate the prevalence of self-reported sleep disturbances in people living with HIV considering the effects of age, depression, anxiety, CD4 cell counts, time since HIV diagnosis, study region, and the instruments used to measure sleep disturbances. We searched PubMed, PsycINFO, and EMBASE to include eligible articles. In this meta-analysis of 43 studies, the pooled prevalence of self-reported sleep disturbances was 52.29% (95% confidence interval 47.69–56.87). The subgroup analyses revealed that variations in the sleep measurements and study region significantly contributed to the observed heterogeneity. In the meta-regression analyses, higher proportions of participants with depression or anxiety and longer times since HIV diagnosis were significantly associated with a higher prevalence of self-reported sleep disturbances after adjusting for mean age. Our findings emphasise the substantial burden of sleep disturbances in people living with HIV and identified comorbid depression and anxiety and the time since HIV diagnosis as significant moderators. These results underscore the importance of considering these factors when designing tailored screening programmes for high-risk patients and implementing early interventions to prevent and mitigate sleep disturbances in people living with HIV.

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