Psychological Issues in Sleep Apnea

Madani, Mansoor; Madani, Farideh; Frank, Marcella

doi:10.1016/j.coms.2010.07.007

Cited by 4 publications

(5 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Poor sleep quality, sleep fragmentation, and intermittent hypoxemia have been proposed to influence mood (17,18,41,43). The positive effect of continues positive airway pressure (CPAP) and oxygen supplementation treatment on psychological symptoms in patients with OSA and comorbid depression indicate that hypoxia might play an important role in depressive symptoms treatment-resistance (38,42,44).…”

Section: U N C O R R E C T E D P R O O Fmentioning

confidence: 99%

“…A recent meta-analysis including 12 studies with a total sample of 570,121, illustrated that the prevalence of OSA in serious mental disorders, including MDD, BD, and schizophrenia was 25.7% and the aggregate prevalence was higher in MDD (36.3%) compared to BD (24.5%) or schizophrenia (15.4%) (11). Furthermore, MDD and OSA share a list of common symptoms, such as excessive daytime sleepiness, fatigue, loss of energy, cognitive dysfunction, irritability, insomnia, feel-ings of hopelessness, helplessness, sadness and decreased quality of life (17,18). The common symptoms of OSA, such as day time sleepiness and fatigue, are not always completely reversible with treatment (19).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Higher Risk for Obstructive Sleep Apnea in Chronic Treatment-Resistant Depression

Khazaie

Alavi-Mehr

Younesi

et al. 2018

Iran J Psychiatry Behav Sci

View full text Add to dashboard Cite

Objectives: Studies have reported a higher risk for obstructive sleep apnea (OSA) in major depressive disorder (MDD). However, the risk of OSA in patients with chronic treatment-resistant depressive symptoms is not well documented worldwide. Hence, the current study assessed the risk of OSA and associated factors in patients with chronic treatment resistant depression (cTRD). Methods: The study recruited 140 Iranian patients with cTRD. All patients completed the Berlin questionnaire, which evaluates the risk of OSA. Additionally, demographic data and history of cardiovascular or metabolic diseases were collected. Pearson's Chi-square test, Fisher's exact test, and independent T-test were used to assess group differences, when appropriate. Results: The study found that 89 of 140 cTRD patients (64%) were at high risk for OSA. Group comparison between cTRD patients (high vs. low risk for OSA) demonstrated that at high risk OSA-cTRD patients had an elevated rate of hypertension, diabetes mellitus, and obesity. Also, age, duration of depression, and duration of treatment were significantly higher in cTRD patients with higher risk compared to those with lower risk for OSA. Conclusions:The results suggest that a noticeable number of patients with cTRD are at high risk for OSA, which is higher than the reported magnitude in the general population. Moreover, hypertension, diabetes mellitus, and obesity are associated with a higher risk for OSA. Also, age, treatment duration, and depression duration could be considered as possible comorbid factors for OSA in patients with cTRD.

show abstract

Section: U N C O R R E C T E D P R O O Fmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Higher Risk for Obstructive Sleep Apnea in Chronic Treatment-Resistant Depression

Khazaie

Alavi-Mehr

Younesi

et al. 2018

Iran J Psychiatry Behav Sci

View full text Add to dashboard Cite

show abstract

“…The risk factors for OSA are shown in Table 1. OSA is not only a disease of the UA, but should be rather approached as a medical condition with systemic features. Indeed, OSA is associated with cardiovascular metabolic diseases such as arterial hypertension, coronary artery disease, heart failure, arrhythmias, stroke, type 2 diabetes mellitus, renal disease and liver disease [2][3][4][5][6][7], as well car accidents and neuropsychiatric disease, which are more common in patients with OSA than in the general population [8,9].…”

Section: Introductionmentioning

confidence: 99%

Physical exercise related improvement in obstructive sleep apnea. Look for the rostral fluid shift

Mirrakhimov

2013

Medical Hypotheses

View full text Add to dashboard Cite

“…Psychiatric disorders commonly seen in patients with FXTAS include anxiety, agitation, apathy, and depression [Bacalman et al, 2006; Bourgeois et al, 2011]. Sleep disorders can exacerbate these behavioral issues [Madani et al, 2010], and are often overlooked in those with FXTAS. Approximately 2% if women and 4% of men are estimated to suffer from sleep apnea, according to conventional diagnostic criteria [Young et al, 1993].…”

Section: Introductionmentioning

confidence: 99%

Sleep apnea in fragile X premutation carriers with and without FXTAS

Hamlin

Liu

Nguyen³

et al. 2011

American J of Med Genetics Pt B

View full text Add to dashboard Cite

This report seeks to establish the prevalence of sleep apnea in patients with the FMR1 premutation with and without FXTAS and to determine any correlation between CGG repeat and FMR1 mRNA levels with sleep apnea prevalence. Demographic and medical data from 430 (229 males, 201 females) participants were used in this analysis. Participants included premutation carriers with (n=118) and without FXTAS (n=174) as well as controls without the premutation (n=123). Logistic regression models were employed to estimate the odds ratio of sleep apnea relative to controls, adjusted for age and gender, and also to examine potential association with CGG size and FMR1 mRNA expression level. The observed proportion of sleep apnea in premutation carriers with and without FXTAS and controls are 31.4% (37/118), 8.6% (15/174), and 13.8% (17/123), respectively. The adjusted odds of sleep apnea for premutation carriers with FXTAS is about 3.4 times that compared to controls (odds ratio, OR=3.4, 95% CI 1.8 to 7.4; p=0.001), and similarly relative to premutation carriers without FXTAS (OR=2.9, 95% CI 1.2 to 6.9; p=0.014). The risk of sleep apnea was not different between controls and premutation carriers without FXTAS. The presence of sleep apnea is not associated with CGG repeat numbers nor FMR1 mRNA expression level among premutation carriers. Our data supports a higher prevalence and risk of sleep apnea in patients with FXTAS. We recommend that all patients diagnosed with FXTAS be screened for sleep apnea given the negative and perhaps accelerative impact sleep apnea may have on their FXTAS progression.

show abstract

Psychological Issues in Sleep Apnea

Cited by 4 publications

References 56 publications

Higher Risk for Obstructive Sleep Apnea in Chronic Treatment-Resistant Depression

Higher Risk for Obstructive Sleep Apnea in Chronic Treatment-Resistant Depression

Physical exercise related improvement in obstructive sleep apnea. Look for the rostral fluid shift

Sleep apnea in fragile X premutation carriers with and without FXTAS

Contact Info

Product

Resources

About