Interpersonal emotion regulation relates to the state of well-being of the people by augmenting work engagement, performance, and limiting the experience of negative emotions in relationships. Vedic tradition considers emotional maturity as the capacity to endure the emotional upheavals in life. But the common belief is that Vedic contemplative practices are for intrapersonal emotional regulation only. Contemporary research needs further conceptual and methodological innovations to facilitate interpersonal emotion regulation through diverse contemplative practices. To this end, the current work has sought to analyze the role and mechanisms of Vedic contemplative practices in improving interpersonal emotion regulation. Also, it illustrates several contemplative activities, used as stand-alone or adjunct, to ameliorate difficulties in relationships. It further illuminates significant neurological mechanisms and theoretical and methodological challenges in research on the promotion of interpersonal emotion regulation through Vedic contemplative techniques.