Psychological distress and self‐management behaviours among patients with chronic hepatitis B receiving oral antiviral therapy

Abstract

Aims To assess the prevalence and associated factors of psychological distress among patients with chronic hepatitis B receiving oral antiviral therapy and explore the association between psychological distress and self‐management behaviours among this population. Design A cross‐sectional study. Methods A convenience sample of 188 patients with chronic hepatitis B receiving oral antiviral therapy was recruited from March‐October 2018 to complete a self‐report questionnaire including the Chinese version of Depression Anxiety Stress Scale‐21 and Chronic Hepatitis B Self‐Management Scale. Logistic regression analysis and hierarchical multiple regression analysis were used to determine the factors associated with psychological distress and the association between psychological distress and self‐management behaviours respectively. Results The prevalence of depression, anxiety, and stress symptoms were 33.0%, 38.3% and 17.6% respectively. Depression was associated with older age, female gender, lower education level and longer treatment duration; anxiety was associated with female gender and longer treatment duration; and stress was associated with age of 31–40 years, female gender and unmarried status. There were significant associations between depression and anxiety symptoms and self‐management behaviours. Conclusion Psychological distress was prevalent among patients with chronic hepatitis B receiving oral antiviral therapy and had a negative impact on self‐management. Interventions targeting depression and anxiety symptoms may be beneficial to improve self‐management behaviours for this population. Impact This study explored the factors associated with psychological distress in patients with chronic hepatitis B receiving oral antiviral therapy. The findings showed psychological distress was more common in patients who were with older age, female, less educated, unmarried and receiving longer duration of treatment and psychological distress was significantly associated with self‐management behaviours. Nurses and other healthcare providers should provide interventions to reduce the risk of psychological distress and improve self‐management behaviours for this population.

Self-Efficacy, Coping Strategies and Quality of Life among Patients with Chronic Hepatitis B

“…Moreover, patients with CHB usually experienced psychological distress. 3 , 4 Patients with higher self-efficacy tend to be more capable of dealing with disease demands and are less affected by negative emotions, benefiting their QoL. Our results further highlight that self-efficacy could be a useful intervention target for improving QoL among patients with CHB.…”

“…The main goal of CHB management is to improve patients’ survival rates and QoL. Patients with CHB usually suffer from a great burden due to the chronic nature of the illness, potentially severe complications, and discrimination in society, 4,6 which may have negative effects on their QoL. In Chen et al’s study, 7 patients with hepatitis B reported lower QoL compared to the general population.…”

“…Current studies have shown that patients with CHB usually experience fatigue, pain, stigma, depression, anxiety, and poor quality of life (QoL). 3,4 Improving QoL has been an important consideration in the care of patients with CHB. Identification of potentially modifiable factors of QoL could assist healthcare providers in developing and implementing effective interventions to improve patients’ QoL.…”

The Application of Nurse Stratified Management in Nursing Management

“…(3) Hierarchical nursing management was implemented based on the ability of nurses to obtain more satisfactory nursing services and better nursing quality. With reference to nurses' clinical experience and educational level, hospitals categorize and implement nursing tasks, optimize human resource allocation, and correctly construct and improve the specific content and process of nursing work, thereby enhancing nursing quality [8]. (4) A management system in line with nursing hierarchical management was established, and specific training programs and assessment standards and reasonable training and assessment systems were formulated based on the specific conditions of each department.…”

Anxiety and Its Influencing Factors in Patients With Drug-Induced Liver Injury

“…Even for high-risk patients with severe mental disorders, direct antiviral therapy had no effect on anxiety or depression during or after treatment for chronic hepatitis C infection ( Gallach et al, 2018 ). Kong et al (2021) showed that the incidence of anxiety increased in patients with chronic hepatitis B treated with oral antiviral therapy, and female gender and length of treatment were high risk factors. The incidence of anxiety and depression in patients with autoimmune hepatitis is also very high ( Schramm et al, 2014 ; Janik et al, 2019 ).…”