Psychological distress and cancer pain: Results from a controlled cross-sectional survey in China

Li, Xiaomei; Xiao, Wenhua; Yang, Ping; Zhao, Huixia

doi:10.1038/srep39397

Cited by 46 publications

(43 citation statements)

References 38 publications

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“…From this point of view, most cancer pain in the present study was not effectively controlled. The main barriers to better pain management in China were reported as inadequate medical knowledge, pain assessment and its management, a very complicated procedure for opioid prescription, and generally low levels of patient compliance for analgesics for fear of addiction, drug tolerance, and adverse effects . The under‐treatment of cancer pain and its influence on psychological distress in this study emphasizes the importance of assessing and managing pain among advanced cancer patients.…”

Section: Discussionmentioning

confidence: 85%

“…One barrier to pain management is lack of relevant psychosocial factors in pain assessment when pain is multidimensional . Many detecting methods had been used among cancer pain patients, such as the Center for Epidemiologic Studies Depression Scale (CES‐D), the Hospital Anxiety and Depression Scale (HADS), Profile of Mood States (POMS), and Beck Depression Inventory‐II (BDI‐II) . The Distress Thermometer (DT) is a widely used distress screening tool for cancer patients, where highly distressed patients are identified by DT scores exceeding the cutoff to get further treatment.…”

Section: Introductionmentioning

confidence: 99%

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The use of distress thermometer in advanced cancer inpatients with pain

et al. 2019

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Objective: This study aimed to provide support for the extensive application of Distress Thermometer (DT) in advanced cancer inpatients with pain and explored factors associated with high DT scores among this population. Methods: Advanced cancer patients with pain were recruited from Department of Pain Relief in Tianjin Cancer Hospital and Institute, China. They completed the DT with problems list and HADS within 48 h after admission. The cutoff score of DT was evaluated against Hospital Anxiety and Depression Scale (HADS) for its sensitivity and specificity by using receiver operating characteristic (ROC) curves. Multiple logistic regression model analysis was performed to investigate correlates of DT scores.Results: Four hundred forty one inpatients with mixed diagnoses were recruited.Referring to the cutoff of 15 on HADS, DT cutoff score of 5 yielded AUC of 0.757, with an optimal sensitivity of 0.861 and specificity of 0.531. Using the cutoff scores of greater than or equal to 5, 70.5% of the patients were distressed. Logistic regression analysis of DT found that the breakthrough pain, poorer KPS, higher pain degree, and emotional problems were the predictive factor for current distress.Conclusion: DT is efficacious in screening for psychological distress in advanced cancer inpatients with pain. Psychological distress is prevalent with a cutoff score of greater than or equal to five. To better identify the distressed cancer patients with pain, pain degree, performance status, and emotional problems should be considered together.

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Section: Discussionmentioning

confidence: 85%

Section: Introductionmentioning

confidence: 99%

The use of distress thermometer in advanced cancer inpatients with pain

et al. 2019

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“…Furthermore, while outside the scope of this review, there are several other diseases and pathologic states possibly linked to oxytocin. Pain, depression, and anxiety have all been linked to oxytocin[ 102 , 103 ]. Oxytocin’s role in depression management was mentioned previously in this article, but oxytocin also seems to be a promising target in pain management[ 104 - 107 ], and in immunotherapy, especially through its interactions in the gut[ 108 ].…”

Section: Oxytocin In Cancermentioning

confidence: 99%

Oxytocin and cancer: An emerging link

Lerman¹,

Harricharran²,

Ogunwobi³

2018

WJCO

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The neuropeptide hormone oxytocin, which is released from the posterior pituitary gland, is involved in a number of physiological processes. Understanding of its effects is gradually increasing due to new research in this area. While mostly recognized as a reproductive system hormone, oxytocin also regulates other organ systems such as the brain and cardiovascular system. Recently, research has focused on unraveling its involvement in cancer, and emerging evidence suggests a potential role for oxytocin as a cancer biomarker. This review summarizes observations linking oxytocin and cancer, with a special emphasis on prostate cancer, where it may promote cell proliferation. Research suggests that oxytocin effects may depend on cell type, concentration of the hormone, its interactions with other hormones in the microenvironment, and the precise localization of its receptor on the cell membrane. Future research is needed to further elucidate the involvement of oxytocin in cancer, and whether it could be a clinical cancer biomarker or therapeutic target.

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“…[ 4 ] These patients with CP also present insomnia, anxiety, depression, and other psychiatric symptoms. [ 5 , 6 ] CP not only diminishes patients quality of life and physical function, [ 7 ] but also incurs economic costs to both their families and to society. [ 8 ]…”

Section: Introductionmentioning

confidence: 99%

Clinical evidence of acupuncture and related therapy in patients with cancer-pain

et al. 2020

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Background: Cancer pain (CP) is one of the common complications of cancer. During the treatment, oral medication, radiotherapy and chemotherapy bring certain adverse reactions to patients with CP; a safe way to treat this disease is necessary. Acupuncture and related therapies for CP with few side effects have been gradually accepted. But at present the evidence is insufficient, the related research is not thorough enough. The purpose of this study was to investigate the efficacy and safety of acupuncture and related therapies for CP. Methods: The Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) guidelines were used to design this protocol. The final study will also be conducted under the PRISMA guidelines for systematic reviews and meta-analysis. An electronic search will be conducted in Medline, Embase, and the Cochrane Central Register of Controlled Trials databases through January 2020. The search will be conducted in English. Risk of bias will be assessed by the Cochrane Collaboration tool and the collected evidence will be nar-ratively synthesized. We will also perform a meta-analysis to pool estimates from studies considered to be homogenous. Subgroup analyses will be based on intervention or overall bias. The strength of evidence will be evaluated by the Grading of Recommendations, Assessment, Development and Evaluation scale. Results: This systematic review will summarize high quality clinical evidence to assess and appraise the effectiveness and safety of acupuncture and related therapies for CP patients. Conclusion: The meta-analysis will assess evidence from randomized controlled trials of acupuncture and related therapies and CP types. INPLASY registration number: INPLASY202040129.

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Psychological distress and cancer pain: Results from a controlled cross-sectional survey in China

Cited by 46 publications

References 38 publications

The use of distress thermometer in advanced cancer inpatients with pain

The use of distress thermometer in advanced cancer inpatients with pain

Oxytocin and cancer: An emerging link

Clinical evidence of acupuncture and related therapy in patients with cancer-pain

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