Psychological defensive profile of sciatica patients with neuropathic pain and its relationship to quality of life

Tutoğlu, Ahmet; Boyacı, Ahmet; Karababa, İbrahim Fatih; Koca, İrfan; Kaya, Edip; Küçük, Ahmet; Yetişgin, Alparslan

doi:10.1007/s00393-014-1527-4

Cited by 11 publications

(8 citation statements)

References 33 publications

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“…The present study shows that patients with NP display a number of differences when compared to age‐ and sex‐matched healthy volunteers. Patients with NP are more depressed and anxious ( P < 0.001) and show a diminished quality of life ( P < 0.001) compared to controls, confirming reports in the literature . Patients with NP also present some degree of cognitive impairment for vigilance, spatial planning/working memory, speed of movement, decision making, risk‐taking behavior, and semantic memory, as already reported in patients with chronic pain .…”

Section: Discussionsupporting

confidence: 86%

Hormonal Status and Cognitivo‐Emotional Profile in Real‐Life Patients With Neuropathic Pain: A Case Control Study

et al. 2019

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& AbstractBackground: The specific impact of neuropathic pain and recommended neuropathic pain treatments on the hormonal and immune status of patients has been so far poorly explored. This study aimed at studying, in real life, the hypothalamic-pituitary-adrenal axis and the cytokine profile of patients with neuropathic pain. It also explored their links with cognition, emotion, quality of life, and drug treatment. Methods: This prospective study (clinicaltrials.gov NCT01543425) included 60 patients with neuropathic pain and 60 age-and gender-matched healthy volunteers after obtaining signatures of informed consent. A number of parameters were measured: adrenocorticotropic hormone, cortisol, cortisol awakening response, dehydroepiandrosterone sulphate, sex hormone binding globulin, testosterone, 17-b-estradiol, progesterone, luteinizing hormone, follicle-stimulating hormone, cytokines, brain-derived neurotrophic factor, and vitamin D. Psychological parameters were assessed by questionnaires. Results: Patients with neuropathic pain had lower levels of adrenocorticotropic hormone (P = 0.009) and dehydroepiandrosterone sulphate (P < 0.001) than controls, and the cortisol awakening response was impaired. Patients were more depressed and anxious (P < 0.001) and had a diminished quality of life (P < 0.001), which was influenced by cytokines (P = 0.0067) and testosterone (P = 0.028). Antidepressants and antiepileptics appeared to interfere with testosterone and cognitivo-emotional domains.

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Section: Discussionsupporting

confidence: 86%

Hormonal Status and Cognitivo‐Emotional Profile in Real‐Life Patients With Neuropathic Pain: A Case Control Study

et al. 2019

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“…In a study on patients with chronic illness, the researchers concluded that patients showed an immature defense and neurological profile (25). Also, in sciatica patients, the findings showed that exponential action of defense-style and depression with pain related to QoL were correlated and in these patients immature and neurotic defensive profile was diagnosed from defense mechanisms (29). Another finding of this study was that excessive use of reaction formation and projection mechanisms are associated with lower levels of QoL in the cognitive and role aspects.…”

Section: Discussionmentioning

confidence: 99%

Relationship Between Defense Mechanisms and the Quality of Life in Women With Breast Cancer

Talepasand

Mahfar

2018

Int J Cancer Manag

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Background: Patients with breast cancer often experience severe psychological distress after awareness of cancer and during the course of treatment, and have lower physical and psychological quality in their life. Objectives: The aim of this study is to investigate the relationship between defense mechanisms in cancer patients with various aspects of their quality of life. Methods:The present study is a correlational study. Participants were 96 women with breast cancer who were referred and hospitalized at Imam Khomeini hospital in Tehran in summer of 2015 and were selected by convenience sampling. They completed defense mechanisms and general quality of life questionnaires. Data were analyzed using canonical correlation model. Results: Two significant canonical functions were identified in data. First canonical function showed that too much use of displacement and regression defense mechanisms are accompanied with low level of quality of life in physical, cognitive and role aspects. Second canonical function showed that too much use of reaction formation and projection defense mechanisms are associated with lower levels of quality of life in cognitive and role aspects. Conclusions: Paying attention to psychological factors and defense mechanisms that are used by cancer patients could help clinical therapists to make very effective mental health interventions.

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“…This is consistent with previous research of patients with and without NP based on clinical examination, [33][34][35] which found fewer differences in pain duration, LBLP-related disability, depression, anxiety, and health-related quality of life between patients with and without NP compared with those research studies using screening tools to identify cases of NP. [36][37][38] None of the previous studies [33][34][35][36][37][38] aimed to describe the characteristics of LBLP patients with or without NP and, in part, were limited by either small sample sizes or poorly defined comparator groups.…”

Section: Discussionmentioning

confidence: 99%

Prevalence, Characteristics, and Clinical Course of Neuropathic Pain in Primary Care Patients Consulting With Low Back-related Leg Pain

Harrisson

Ogollah

Dunn

et al. 2020

The Clinical Journal of Pain

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Objectives: Little is known about the epidemiology of neuropathic pain in primary care patients consulting with low back-related leg pain. We aimed to describe prevalence, characteristics, and clinical course of low back-related leg pain patients with and without neuropathic pain, consulting with their family doctor in the United Kingdom. Materials and Methods: This was a prospective cohort study. Data were collected using a standardized baseline clinical examination and self-report questionnaires at baseline, 4, 12, and 36 months. We identified cases of neuropathic pain using 3 definitions: 2 based on clinical diagnosis (sciatica, with and without evidence of nerve root compression on magnetic resonance imaging), one on the self-report version of Leeds Assessment for Neurological Symptoms and Signs. Differences between patients with and without neuropathic pain were analyzed comparing each definition. Clinical course (mean pain intensity measured as the highest of leg or back pain intensity: mean of 3 Numerical Rating Scales, each 0 to 10) was investigated using linear mixed models over 36 months. Results: Prevalence of neuropathic pain varied from 48% to 74% according to definition used. At baseline, patients with neuropathic pain had more severe leg pain intensity, lower pain self-efficacy, more patients had sensory loss than those without. Distinct profiles were apparent depending on neuropathic pain definition. Mean pain intensity reduced after 4 months (6.1 to 3.9 [sciatica]), most rapidly in cases defined by clinical diagnosis. Discussion: This research provides new information on the clinical course of neuropathic pain and a better understanding of neuropathic pain in low back-related leg pain patients consulting in primary care.

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Psychological defensive profile of sciatica patients with neuropathic pain and its relationship to quality of life

Abstract: The acting out defensive style and BDI were independently associated with pain-related quality of life. In the SNP group, significant differences were found in the immature and neurotic styles of the defense mechanisms.

Cited by 11 publications

References 33 publications

Hormonal Status and Cognitivo‐Emotional Profile in Real‐Life Patients With Neuropathic Pain: A Case Control Study

Hormonal Status and Cognitivo‐Emotional Profile in Real‐Life Patients With Neuropathic Pain: A Case Control Study

Relationship Between Defense Mechanisms and the Quality of Life in Women With Breast Cancer

Prevalence, Characteristics, and Clinical Course of Neuropathic Pain in Primary Care Patients Consulting With Low Back-related Leg Pain

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