Psychological correlates of sleep quality in lung cancer patients under chemotherapy: A single‐center cross‐sectional study

Abstract

Objectives: Disturbed sleep is a common complaint of lung cancer patients undergoing active oncologic treatment. We aimed to clarify the extent to which psychological symptoms, coping strategies, and social support interfere with sleep quality and whether they mediate the relationship between sleep quality and fatigue or functional capacity in a sample of chemotherapy treated lung cancer patients.Methods: Lung cancer patients attending an oncology unit for scheduled chemotherapy cycles completed questionnaires assessing their sleep quality, fatigue, depression, anxiety, stress, coping, social support, symptoms of pain, dyspnea, and cough, and sleep hygiene practices. Demographic and disease-related characteristics were obtained from patients' medical records and treating physicians rated their functional status. Multivariate regression and mediation analyses were applied to test the study's hypotheses. Results: One hundred nineteen patients were enrolled, 58.2% of whom were identified as poor sleepers. After adjusting for age, gender, comorbidities, concomitant medications, cancer stage, prior and ongoing treatment, sleep hygiene, and symptoms, there was a statistically significant association between poor sleep quality and anxiety (odd`s ratio [OR] 1.17 [95% CI, 1.01-1.35]), stress (OR 1.14 [95% CI, 1.04-1.25]), and positive coping (OR 1.15 [95% CI, 1.02-1.31]). Poor sleep quality was an independent correlate of fatigue (B 1.56 [95% CI, 0.61-2.50]) and low performance status (OR 5.17 [95% CI,); stress symptoms partially mediated the relationship between sleep quality and fatigue (P = .030). Conclusions:Higher psychological burden predict sleep disturbances and contribute to increased fatigue in lung cancer patients undergoing chemotherapy. Effective psychoeducational interventions may benefit these populations.

Insomnia in patients with advanced lung cancer admitted to palliative care services

“…Most data regarding sleep disorders are gathered from patients who were diagnosed lung cancer, were undergoing chemotherapy, or were long-survivors. [14][15][16][17] Studies have reported a high psychological burden affecting quality of life. 18 Of interest, sleep quality was found to be prognostic factor for survival.…”

Profiling Patient-Reported Symptom Recovery from Esophagectomy for Patients with Esophageal Squamous Cell Carcinoma: A Real World Longitudinal Study

“…Distress and disturbed sleep are two common persistent symptoms [37,38], and higher psychological distress can predict sleep disturbances [39,40]. Our results revealed that although the peak scores for sleep and psychological symptoms were not particularly high, distress and disturbed sleep persisted before surgery to 90 days after surgery; at 90 days after surgery, approximately 50.58% of patients still reported sleep disturbances.…”

Staged versus conventional nursing for patients receiving chemotherapy for advanced non-small cell lung cancer: a before and after study

“…Although graded nursing did not exhibit any significant impact on the incidence of adverse events, it still significantly improved the QoL of NSCLC patients in our study. There are a number of previously published studies exploring efficient measurements to improve the QoL of NSCLC patients (19)(20)(21)(22)(23)(24)(25)(26)(27). The co-administration of conventional chemotherapeutic agents and novel drugs provides an option.…”