Objective and Methods:
Given associations between stress, and gastrointestinal (GI) symptoms and disorders, this pilot study assesses relationships between perceived stress, quality of life (QOL) and self-reported pain ratings as an indicator of symptom management in patients who self-reported gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).
Results:
In a sample of GI patients (n=402), perceived stress positively correlated with depression (r=0.76, p<0.0001), fatigue (r=0.38, p< 0.0001), sleep disturbance (r=0.40, p<0.0001), average pain (r=0.26, p<0.0001) and worst pain (r=0.25, p< 0.0001). Higher perceived stress also correlated with lower mental health-related QOL. Assessed in subgroups, similar correlations were found for the participants with GERD (n=188), IBS (n=132) and IBD (n=82). Finally, there were significant correlations within both the GERD and IBD cohorts between perceived stress, and average pain (r=0.34, p<0.0001; r=0.32, p<0.0001respectively) and worst pain (r=0.29, p<0.0001; r=0.35, p<0.01respectively).
Conclusions:
Perceived stress broadly correlated with QOL characteristics in patients with GERD, IBS, and IBD, and their overall QOL was significantly lower than that of the general population. Perceived stress also appeared to be an indicator of symptom management (self-reported pain ratings) in GERD and IBD, but not IBS. Future research is needed using objective measures of stress and symptom/disease management to confirm these associations, and to prospectively evaluate the ability of stress reduction interventions to improve perceived stress, QOL and disease management in these GI disorders; integrative medicine treatment programs that simultaneously target such multiple symptoms may be particularly beneficial to study.