Psychological and clinical-epidemiological profile of poisoning in Nepal: an institutional experience

Basnet, Angela; Shrestha, Dhan Bahadur; Chaulagain, Sabin; Thapa, Ashok; Khadka, Manoj; Regmi, Bishal; Khadka, Manita; Adhikari, Kabita; Thapa, Ajit; Pokharel, Sakar; Singh, Kamla; Syangtang, Prajwal; Adhikari, Surakchha

doi:10.12688/f1000research.54327.2

Cited by 3 publications

(3 citation statements)

References 31 publications

(32 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The negative prognostic value of pleural effusion was similar in other types of viral pneumonia 9 . During two years of the COVID-19 pandemic, there were numerous cases of pleural empyema after confirmation of the SARS-CoV-2 infection described in the literature [10][11][12][13][14][15][16] . Only one case described pleural empyema in a patient who underwent the pulmectomy, which ended fatally (hemorrhagic stroke in the third week of treatment).…”

Section: Discussionmentioning

confidence: 99%

“…Slična negativna prognostička vrednost prisustva EP opisana je i kod nekih drugih pneumonija virusne etiologije 9 . U toku dve godine trajanja Kovid-19 pandemije u literaturi je opisano više slučajeva empijema pleure nakon potvrđene infekcije virusom SARS-CoV-2 [10][11][12][13][14][15][16] . Samo u jednom od njih opisan je empijem kod pulmektomisane osobe, i završio se smrtnim ishodom (hemoragijski inzult u trećoj nedelji lečenja), ali je u pitanju bila Kovid-19 infekcija neposredno nakon pulmektomije zbog malignog procesa na plućima 17 .…”

Section: Diskusijaunclassified

See 1 more Smart Citation

Pleural empyema as a complication of COVID 19 pneumonia in a patient with destroyed lung syndrome

Glavinić-Mijić,

Popović,

Simić-Milovanović

2023

Opšta medicina

View full text Add to dashboard Cite

Introduction. Destroyed lung syndrome is a severe destruction of the pleural parenchyma due to lung infection, mostly caused by tuberculosis. Besides tuberculosis, necrotizing pneumonia may also lead to this disease complication. Pleural empyema is a frequent consequence of the destroyed lung syndrome. Pleural empyema may occur during the COVID-19 infection and is negatively correlated with a favorable disease outcome. Case report. A male 50 y/o showed up during the on-call shift during the winter COVID-19 wave with a medical report from the Internal medicine clinic. His personal history is significant for his pneumonectomy in 2016. In the past two months, he had been treated for pneumonia and COVID-19 infection with antibiotics and corticosteroid therapy. Due to prolonged malaise and tachycardia his GP referred him to yet another chest X-ray and lab work. The chest X-ray showed pleural effusion, so he was promptly referred to an on-call hospital. The on-call physician, after looking into the hospital reports, consulted an internal medicine doctor and it was decided to refer the patient to a thoracic surgeon. He was hospitalized for pleural empyema and treated with thoracic drainage using the system of active aspiration. A year later, he feels well, and he regained his appetite, and body mass, with occasional leaking from the thoracic fistule. Conclusion. This case report shows a recurrence of pleural empyema in a patient with pneumonectomy due to necrotizing pneumonia and destroyed lung syndrome, complicated by COVID-19 infection. We aimed to draw the attention of GPs to diseases and disease complications that are rarely met in GP practice and are not otherwise treated on the primary healthcare level.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Diskusijaunclassified

Pleural empyema as a complication of COVID 19 pneumonia in a patient with destroyed lung syndrome

Glavinić-Mijić,

Popović,

Simić-Milovanović

2023

Opšta medicina

View full text Add to dashboard Cite

show abstract

“…Poisoning is the second most common method of suicide in Nepal, 1 and over 24% of these suicides in Nepal are due to ingestion of highly concentrated agricultural pesticides 2 mostly Organophosphorus (OP). 3 OP are commonly used for agriculture and domestic pest control which may lead to poisoning by unsafe use, accidental drinking, or suicide attempts, especially in farming areas. 4 , 5 Bardiya is in the midwestern part of Nepal where most people are engaged in agriculture, so OP are easily available, and it is the preferred means for poisoning.…”

Section: Introductionmentioning

confidence: 99%

Organophosphorus Poisoning among Acute Poisoning Cases Presenting to the Emergency Department of a Secondary Care Centre: A Descriptive Cross-sectional Study

Pandey¹,

Shrestha²

2022

J Nepal Med Assoc

View full text Add to dashboard Cite

Introduction: Organophosphorus is an easily available compound, especially in agriculture and farming related areas. This study evaluated organophosphorus poisoning among the population in those high-risk areas. The main objective of this study is to find out the prevalence of organophosphorus poisoning among acute poisoning cases presenting to the Emergency Department of a secondary care centre. Methods: A descriptive cross-sectional study was conducted among 427 patients presenting to the Emergency Department in a secondary care centre from 17th July, 2018 to 14th January, 2022. Ethical clearance was taken from the Institutional Review Committee (Reference number: 01/2075-76). All the patients presenting to the Emergency Department were included and the patients without consent, patients with trauma, accident, severe illness and other emergency conditions were excluded. A convenience sampling was done. Data were collected and entered in Microsoft Excel version 2007 and analyzed using Statistical Package for the Social Science version 25.0. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data. Results: Out of 427 patients, 203 (47.54%) (42.80-52.28 at 95% Confidence Interval) had organophosphorus poisoning. It was most commonly seen in the age group 16-30 years among 103 (50.74%). Conclusions: The prevalence of organophosphorus poisoning in our study was similar when compared to other studies conducted in similar settings. Most of the organophosphorus poisoning cases were intentional and suicidal which is similar to other studies.

show abstract

Lambda-cyhalothrin ingestion: an infrequent yet concerning presentation of pyrethroid poisoning

Silwal,

Adhikari,

Yadav

et al. 2023

Annals of Medicine &Amp; Surgery

View full text Add to dashboard Cite

Introduction and importance: Lambda-cyhalothrin is a type II pyrethroid compound commonly used as a pesticide, with the potential to cause life-threatening toxicity in humans. Furthermore, among cases of pesticide poisoning in Nepal, organophosphates are most frequently implicated. Case presentation: A 40-year-old female presented to our hospital after ingesting a pesticide compound with suicidal intent. She also admitted to alcohol intoxication and exhibited symptoms of confusion, abdominal pain, nausea, and vomiting. An atropine challenge test yielded negative results. Therefore, conservative management was continued. It was discovered later that the ingested pesticide was lambda-cyhalothrin. The patient’s condition eventually improved with supportive treatment. Clinical discussion: Several reports have highlighted the overlapping clinical features between organophosphorus and pyrethroid poisoning. In some cases of pyrethroid poisoning, misdiagnosis as organophosphorus poisoning has occurred, leading to the inappropriate administration of atropine. In our case, initial management was challenging owing to the lack of accurate information about the ingested compound. On further evaluation, cholinergic clinical features were absent and the atropine challenge test was negative. This was suggestive of nonorganophosphorus compound poisoning. Conclusion: This case illustrates that managing pesticide poisoning becomes challenging when the nature of the pesticide is unknown. Patients suffering from poisoning caused by pyrethroid compounds like lambda-cyhalothrin can present with features resembling organophosphorus poisoning. In such circumstances, a comprehensive clinical evaluation should guide the management. Clinical features and an atropine challenge test can aid in differentiating organophosphorus from nonorganophosphorus compound poisoning. This distinction facilitates therapeutic decision-making, including the consideration of atropine administration.

show abstract

Psychological and clinical-epidemiological profile of poisoning in Nepal: an institutional experience

Cited by 3 publications

References 31 publications

Pleural empyema as a complication of COVID 19 pneumonia in a patient with destroyed lung syndrome

Pleural empyema as a complication of COVID 19 pneumonia in a patient with destroyed lung syndrome

Organophosphorus Poisoning among Acute Poisoning Cases Presenting to the Emergency Department of a Secondary Care Centre: A Descriptive Cross-sectional Study

Lambda-cyhalothrin ingestion: an infrequent yet concerning presentation of pyrethroid poisoning

Contact Info

Product

Resources

About