Psychogenic nonepileptic seizures

Brown, Richard J.; Syed, Tanvir U.; Benbadis, Selim R.; LaFrance, W. Curt; Reuber, Markus

doi:10.1016/j.yebeh.2011.02.016

Cited by 93 publications

(86 citation statements)

References 96 publications

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Section: Impact Of Pnesmentioning

confidence: 99%

“…Patients are also exposed to iatrogenic procedures, such as high doses of AEDs, intravenous AED use, and orotracheal intubation 21 . Quality of life (QoL) measures in patients with PNES reveal that QoL is worse than that of patients with refractory epilepsyand that QoL is related to symptoms and depression 21 . The diagnostic delay in PNES patients has been reported in the past an average of 7.2 years, however, with increasing awareness of PNES by providers and patients with seizures, and the increased access to seizure monitoring units, the time to correct diagnosis is decreasing, considerably 21 .…”

Section: Impact Of Pnesmentioning

confidence: 99%

“…Likewise, PNES may be considered because of atypical, multiple, inconsistent or changing seizure patterns, or when the seizures are provoked by evident and specific emotional stress, with a narrow temporal relation to seizure occurrence 21,22 . Table 1 summarizes important clinical semiologic features of PNES that help distinguish it from epileptic seizures.…”

Section: Clinical Path To Diagnosis Of Pnesmentioning

confidence: 99%

See 2 more Smart Citations

Psychogenic nonepileptic seizures and psychogenic movement disorders: two sides of the same coin?

Paola

Marchetti

Teive

et al. 2014

Arq. Neuro-Psiquiatr.

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Psychogenic nonepileptic seizures (PNES) and psychogenic movement disorders (PMD) are commonly seen in Neurology practice and are categorized in the DSM-5 as functional neurological disorders/conversion disorders. This review encompasses historical and epidemiological data, clinical aspects, diagnostic criteria, treatment and prognosis of these rather challenging and often neglected patients. As a group they have puzzled generations of neurologists and psychiatrists and in some ways continue to do so, perhaps embodying and justifying the ultimate and necessary link between these specialties.Keywords: psychogenic nonepileptic seizures, psychogenic movement disorders, conversion disorder, hysteria. RESUMOCrises não-epilépticas psicogênicas (CNEP) e distúrbios do movimento psicogênicos (DMP) são comuns na prática e na atualidade são melhor categorizados no DSM-V como distúrbios neurológicos funcionais/desordens de conversão. Esta revisão enfatiza os principais dados históricos, epidemiológicos, clínicos, critérios diagnósticos, tratamento e o prognóstico destes pacientes, frequentemente negligenciados e desafiadores, os quais, como um grupo, tem intrigado gerações de neurologistas e psiquiatras, caracterizando, de forma justificada o elo definitivo entre estas especialidades.Palavras-chave: crises não-epilépticas psicogênicas, distúrbios do movimento psicogênicos, distúrbio conversivo, histeria.In the medical sciences, a diagnosis is established when a level of certainty regarding the nature of a condition is achieved. Psychogenic nonepileptic seizures (PNES) and psychogenic movement disorders (PMD) share a slightly less linear diagnostic route. Historically, making a conversion diagnosis required ruling out the originally considered medical diagnosis, i.e., it is neither epilepsy, nor a neurogenic movement disorder. Only then a non-neurologic (in the sense of not resulting from epileptogenic or known motor circuitry imbalance) condition is suspected and raised to the level of diagnosis 1 . This kind of diagnosis has intrigued generations of physicians and spared no culture, gender or age. A diversity of symptoms, including motor, sensory, cognitive, and/or behavior symptoms are present in these presentations. Patients with PNES or PMD frequently are misdiagnosed as having their initial suspected neurological diseases, and ultimately pose a diagnostic and treatment challenge to many clinicians. Interestingly, it was perhaps this varied presentation that has captured the attention of many professionals through the centuries and lead to the construction and recognition of a very particular diagnosis. Two rather advanced historic civilizations, Egyptians first, and then the Greeks, posited that a displaced hystera (womb), and the consequent suffocation that it produced, was the source of choking, mutism, paralysis and fainting 1 . Hysteria, a natural development on this concept, was claimed as an explanation for similar phenomena in women and reached almost epidemic proportions in the late 19 th century. By th...

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Section: Impact Of Pnesmentioning

confidence: 99%

Section: Impact Of Pnesmentioning

confidence: 99%

Section: Clinical Path To Diagnosis Of Pnesmentioning

confidence: 99%

See 1 more Smart Citation

Psychogenic nonepileptic seizures and psychogenic movement disorders: two sides of the same coin?

Paola

Marchetti

Teive

et al. 2014

Arq. Neuro-Psiquiatr.

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“…Psychogenic seizures (PSs) embrace an extensive range of paroxysmal episodes of impaired self-control associated with a range of motor, sensory, autonomic, and mental manifestations, similar to that of epileptic disorders, yet without underlying epileptic activity [1][2][3]. Psychogenic seizures may appear in patients with epilepsy in addition to epileptic seizures (ESs) and in otherwise healthy individuals.…”

Section: Introductionmentioning

confidence: 99%

Neural generators of psychogenic seizures: Evidence from intracranial and extracranial brain recordings

Arzy

Halje

Schechter

et al. 2014

Epilepsy & Behavior

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Psychogenic seizures (PSs) convincingly mimic seizure phenomena but with no underlying epileptic activity. However, not much is known about their neurophysiological basis. We had the rare opportunity to analyze intracranial brain recordings of PSs occurring besides epileptic seizures (ESs), which identified distinct frequency changes over the parietal cortex. For further validation, we applied topographic frequency analysis to two other patients who presented PSs and ESs during long-term monitoring. The analysis revealed a power decrease in the theta band at the posterior parietal cortex in all three patients during PSs but not during ESs. These changes may reflect disturbed self-referential processing associated with some PSs.

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“…Дакле, и у нашој студији, аналогно резултатима само једне до сада урађене студије (361), је апострофиран став да ФРЕ и ПНЕН, иако по патофизиологији не-сродни поремећаји, својом феноменологијом и коморбидитетима једнако тешко ре-мете све параметре квалитета живота и да представљају тешке болести које у вели-ком броју здравствених и психосоцијалних домена ремете живот (363). Компарабил-ни степен оштећења квалитета живота је показан и при анализи исхода болесника са-мо са ПНЕН (364).…”

Section: скорови квалитета живота (Qolie-31)unclassified

Evaluation of the quality of life of patients with epilepsy and patients with physchogenic non-epileptic seizures

Skrijelj¹

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Psychogenic nonepileptic seizures

Cited by 93 publications

References 96 publications

Psychogenic nonepileptic seizures and psychogenic movement disorders: two sides of the same coin?

Psychogenic nonepileptic seizures and psychogenic movement disorders: two sides of the same coin?

Neural generators of psychogenic seizures: Evidence from intracranial and extracranial brain recordings

Evaluation of the quality of life of patients with epilepsy and patients with physchogenic non-epileptic seizures

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