Psychoedukation bei Sucht und Psychose

Schmeisser, Ulrike; Härtel-Petri, Roland; Rodler, Ramon; Steinmann, J.; Wolfersdorf, M.

doi:10.1055/s-0038-1627271

Cited by 2 publications

(2 citation statements)

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“…193 A European study documented recent increases in hospital admissions for amphetamine-induced paranoid psychosis. 194 After the first occurrence, paranoid symptoms can be invoked by psychosocial stress, but also readily reappear after amphetamine injection. This behavioral sensitization is thought to be mediated by catecholaminergic supersensitivity.…”

Section: Amphetamine Psychosismentioning

confidence: 99%

Potential adverse effects of amphetamine treatment on brain and behavior: a review

et al. 2008

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Rationale Amphetamine stimulants have been used medically since early in the twentieth century, but they have a high abuse potential and can be neurotoxic. Although they have long been used effectively to treat attention deficit hyperactivity disorder (ADHD) in children and adolescents, amphetamines are now being prescribed increasingly as maintenance therapy for ADHD and narcolepsy in adults, considerably extending the period of potential exposure. Effects of prolonged stimulant treatment have not been fully explored, and understanding such effects is a research priority 1. Because the pharmacokinetics of amphetamines differ between children and adults, reevaluation of the potential for adverse effects of chronic treatment of adults is essential. Findings Despite information on the effects of stimulants in laboratory animals, profound species differences in susceptibility to stimulant-induced neurotoxicity underscore the need for systematic studies of prolonged human exposure. Early amphetamine treatment has been linked to slowing in height and weight growth in some children. Because the number of prescriptions for amphetamines has increased several-fold over the past decade, an amphetamine-containing formulation is the most commonly prescribed stimulant in North America, and it is noteworthy that amphetamines are also the most abused prescription medications. Although early treatment does not increase risk for substance abuse, few studies have tracked the compliance and usage profiles of individuals who began amphetamine treatment as adults. Overall, there is concern about risk for slowed growth in young patients who are dosed continuously, and for substance abuse in patients first medicated in late adolescence or adulthood. Although most adult patients also use amphetamines effectively and safely, occasional case reports indicate that prescription use can produce marked psychological adverse events, including stimulant-induced psychosis. Assessments of central toxicity and adverse psychological effects during late adulthood and senescence of adults who receive prolonged courses of amphetamine treatment are warranted. Finally, identification of the biological factors that confer risk and those that offer protection are also needed to better specify the parameters of safe, long-term, therapeutic administration of amphetamines to adults.

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Section: Amphetamine Psychosismentioning

confidence: 99%

Potential adverse effects of amphetamine treatment on brain and behavior: a review

et al. 2008

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“…Most on-label CNS side effects are hyperactivity, insomnia, anorexia, growth retardation, irritability, emotional labiality, social withdrawal as well as psychosis. Not only high doses of amphetamine are associated with psychosis, normal therapeutic dose (5-10 mg) after repeated exposure can also produced psychosis marked with delusion and hallucination in healthy volunteers [14][15][16]. Similarly, in another study, amphetamine 10 mg when taken for 5 weeks precipitated acute symptoms of psychosis in ADHD patients without any personal or family history of psychiatric disorder [17].…”

Section: Introductionmentioning

confidence: 95%

Prescription medication-induced psychosis: A high alert for drug experts

Taslim¹,

Edge²

2020

JCP

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Psychosis is a complex mental illness of behavioral, psychological, and emotional disturbances. Secondary psychosis can be elicited by prescription medications and literature is replete with examples of such drugs. Objectives: The goal of this article is to gather information from multiple published sources to highlight the culprit prescription medications that are linked with psychotic episodes and compose the findings into a simplified, standalone publication for readers to conveniently become aware of this phenomenon. It is also intended to reiterate the critical role and significance of the pharmacist as a vital player in a health care team. Methods: The scientific literature was searched on the PubMed database using the key search phrase “psychosis, medicines or drug or prescription.” The search was limited to the time period from 1960-2019 to ensure the inclusion of the vast majority of previously reported cases of currently available medicines and their related psychoses. Conclusion: Commonly prescribed medications can cause serious, albeit preventable, psychiatric issues. Pharmacists as vital players in patient care can avert the untoward psychotic episode by taking timely steps in notifying the prescribers or counseling the patient on measures to avoid serious and fatal psychotic issues.

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Psychoedukation bei Sucht und Psychose

Cited by 2 publications

References 0 publications

Potential adverse effects of amphetamine treatment on brain and behavior: a review

Potential adverse effects of amphetamine treatment on brain and behavior: a review

Prescription medication-induced psychosis: A high alert for drug experts

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