Psychobiotics, gut microbiota and fermented foods can help preserving mental health

Casertano, Melania; Fogliano, Vincenzo; Ercolini, Danilo

doi:10.1016/j.foodres.2021.110892

Cited by 29 publications

(16 citation statements)

References 74 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The diversity and density of gut microbiota are sensitive to the factors including diet, stress, and aging; thereby, chronic alcohol intake would dramatically disturb the gut microbial population. Theoretically, the agents targeting gut microbiota might be considered potential cognitive enhancers and the gaining popularity of fermented foods is largely ascribed to the possible preventive or therapeutic effect on the brain dysfunction . The regulation of food-derived hydrolysates on the gut microbial population has been increasingly reported so far .…”

Section: Resultsmentioning

confidence: 99%

“…Theoretically, the agents targeting gut microbiota might be considered potential cognitive enhancers and the gaining popularity of fermented foods is largely ascribed to the possible preventive or therapeutic effect on the brain dysfunction. 43 The regulation of food-derived hydrolysates on the gut microbial population has been increasingly reported so far. 44 However, the modulation of TCH on the gut microbial population has not been elucidated in the present study, and this limitation will be systematically investigated in the future.…”

Section: Assay Of Synaptic Plasticity In Hippocampusmentioning

confidence: 99%

See 1 more Smart Citation

Theragra chalcogramma Hydrolysates, Rich of Fragment Gly-Leu-Pro-Ser-Tyr-Thr, Ameliorate Alcohol-Induced Cognitive Impairment via Attenuating Neuroinflammation and Enhancing Neuronal Plasticity in Sprague–Dawley Rats

Zhao

2022

J. Agric. Food Chem.

View full text Add to dashboard Cite

Chronic alcohol abuse induces the cognitive deficits and is associated with low-grade inflammation and neurodegeneration. Currently, by virtue of the immunomodulatory and neuroprotective properties, nutrients represent a promising strategy to attenuate cognitive impairments. We previously prepared the hydrolysates from Theragra chalcogramma skin (TCH), and this study aims to evaluate the neuroprotection of TCH on alcohol-induced cognitive impairment (AICI) and to elucidate the associated mechanism. Behavioral results showed that TCH effectively ameliorated AICI and this amelioration was highly associated with the decrease of IL-1β and the increase of BDNF, CREB, and PSD95 in AICI rats (P < 0.05). Furthermore, TCH restored the histopathological impairment in hippocampus by reactivating extracellular signal-regulated kinase and suppressing Caspase-3 apoptosis signal pathways and modulating the abnormality of neurotransmitters acetylcholine and γ-aminobutyric acid(P < 0.05 or 0.01). Therefore, TCH exhibits potent attenuation of neuroinflammation and represents a potential ingredient for prevention of AICI.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Assay Of Synaptic Plasticity In Hippocampusmentioning

confidence: 99%

Theragra chalcogramma Hydrolysates, Rich of Fragment Gly-Leu-Pro-Ser-Tyr-Thr, Ameliorate Alcohol-Induced Cognitive Impairment via Attenuating Neuroinflammation and Enhancing Neuronal Plasticity in Sprague–Dawley Rats

Zhao

2022

J. Agric. Food Chem.

View full text Add to dashboard Cite

show abstract

“…Thus, psychobiotics can directly influence many of the pathophysiological mechanisms involved in MDD, modulating the HPA axis, inflammation, neurotransmitter production (monoamines, GABA, glutamate, and acetylcholine), BDNF levels, as well as host metabolism and systemic actions via the vagus nerve or through critical microbial metabolites such as SCFAs [ 154 ]. Psychobiotics are mainly represented by lactic acid bacteria (LAB), bacteria from the order of Lactobacillales and Bifidobacteria [ 155 ], which they can be found in supplements—using single or multispecies formulas—or included in fermented foods and beverages such as in dairy products (yogurt and kefir), soy derivates (i.e., tempeh), and other products [ 156 ]. In this section, we will explore some of the most relevant psychobiotic potential of fermented food and beverages.…”

Section: Translational Opportunities: Clinical Management Of Mdd Thro...mentioning

confidence: 99%

Biological Role of Nutrients, Food and Dietary Patterns in the Prevention and Clinical Management of Major Depressive Disorder

et al. 2022

View full text Add to dashboard Cite

Major Depressive Disorder (MDD) is a growing disabling condition affecting around 280 million people worldwide. This complex entity is the result of the interplay between biological, psychological, and sociocultural factors, and compelling evidence suggests that MDD can be considered a disease that occurs as a consequence of an evolutionary mismatch and unhealthy lifestyle habits. In this context, diet is one of the core pillars of health, influencing multiple biological processes in the brain and the entire body. It seems that there is a bidirectional relationship between MDD and malnutrition, and depressed individuals often lack certain critical nutrients along with an aberrant dietary pattern. Thus, dietary interventions are one of the most promising tools to explore in the field of MDD, as there are a specific group of nutrients (i.e., omega 3, vitamins, polyphenols, and caffeine), foods (fish, nuts, seeds fruits, vegetables, coffee/tea, and fermented products) or dietary supplements (such as S-adenosylmethionine, acetyl carnitine, creatine, amino acids, etc.), which are being currently studied. Likewise, the entire nutritional context and the dietary pattern seem to be another potential area of study, and some strategies such as the Mediterranean diet have demonstrated some relevant benefits in patients with MDD; although, further efforts are still needed. In the present work, we will explore the state-of-the-art diet in the prevention and clinical support of MDD, focusing on the biological properties of its main nutrients, foods, and dietary patterns and their possible implications for these patients.

show abstract

“…In recent decades, the relationship between food, health, and microbiota (mainly intestinal) has begun to be established, in which the consumption of a “Western diet” based on foods with a high content of rapidly assimilated sugars, a high quantity of animal proteins and a large proportion of fats produces an imbalance in intestinal populations, with an alteration of the microbial ecosystem at the population and functional level, resulting in health problems associated with early inflammatory and degenerative processes [ 187 ]. In the same way, that adherence to a Mediterranean diet, varied in vegetables, legumes, fruits, meat and fish, allows for maintaining a healthy microbiota with complete functionality associated with disease prevention, stimulation of the host’s immune system, neuromodulation, and improvement in the acquisition of nutrients [ 188 ].…”

Section: Impact On Gut Microbiomementioning

confidence: 99%

Cherries and Blueberries-Based Beverages: Functional Foods with Antidiabetic and Immune Booster Properties

et al. 2022

View full text Add to dashboard Cite

Nowadays, it is largely accepted that the daily intake of fruits, vegetables, herbal products and derivatives is an added value in promoting human health, given their capacity to counteract oxidative stress markers and suppress uncontrolled pro-inflammatory responses. Given that, natural-based products seem to be a promising strategy to attenuate, or even mitigate, the development of chronic diseases, such as diabetes, and to boost the immune system. Among fruits, cherries and blueberries are nutrient-dense fruits that have been a target of many studies and interest given their richness in phenolic compounds and notable biological potential. In fact, research has already demonstrated that these fruits can be considered functional foods, and hence, their use in functional beverages, whose popularity is increasing worldwide, is not surprising and seem to be a promising and useful strategy. Therefore, the present review reinforces the idea that cherries and blueberries can be incorporated into new pharmaceutical products, smart foods, functional beverages, and nutraceuticals and be effective in preventing and/or treating diseases mediated by inflammatory mediators, reactive species, and free radicals.

show abstract

Psychobiotics, gut microbiota and fermented foods can help preserving mental health

Cited by 29 publications

References 74 publications

Theragra chalcogramma Hydrolysates, Rich of Fragment Gly-Leu-Pro-Ser-Tyr-Thr, Ameliorate Alcohol-Induced Cognitive Impairment via Attenuating Neuroinflammation and Enhancing Neuronal Plasticity in Sprague–Dawley Rats

Theragra chalcogramma Hydrolysates, Rich of Fragment Gly-Leu-Pro-Ser-Tyr-Thr, Ameliorate Alcohol-Induced Cognitive Impairment via Attenuating Neuroinflammation and Enhancing Neuronal Plasticity in Sprague–Dawley Rats

Biological Role of Nutrients, Food and Dietary Patterns in the Prevention and Clinical Management of Major Depressive Disorder

Cherries and Blueberries-Based Beverages: Functional Foods with Antidiabetic and Immune Booster Properties

Contact Info

Product

Resources

About