Psychiatrische Komorbidität bei Hidradenitis suppurativa/Acne inversa

Mavrogiorgou, Paraskevi; Juckel, Georg; Reimelt, Andreas; Hessam, Schapoor; Scholl, Lisa; Frajkur, Jessica Lisa; Stockfleth, Eggert; Bechara, Falk G.

doi:10.1007/s00105-020-04742-9

Cited by 2 publications

(2 citation statements)

References 53 publications

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“…In a prospective study with 51 patients with HS, 29.4% presented mental symptoms, mainly symptoms of depressive disorder. HS patients were predominantly young, female, with a history of high incidence of nicotine and alcohol use, a positive family history of paternal alcohol dependence, and with more serious psychosocial impairments such as less education [197]. In a cross-sectional study involving 1,795 patients, pain was reported in 83.6% of cases.…”

Section: Hidradenitis Suppurativa and Mental Health (Psychiatric Dise...mentioning

confidence: 99%

Qualitative Systematic Review on the Bio-Psycho-Socioeconomic Impact of Hidradenitis Suppurativa/Acne Inversa

Augusto,

Monica,

Giulia

et al. 2024

J Surgery

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Hidradenitis Suppurativa or Acne Inversa (HS) is a chronic, inflammatory, recurrent integumentary disease, with periods of exacerbation, related to metabolic comorbidities, affecting the well-being, quality of life and mental health of patients, in addition to negatively influencing oral health and women’s health levels as well. It often presents little responsiveness to conventional dermatological treatments. With the aim of estimating the biopsychosocial and economic impact on patients’ lives, a qualitative systematic review was planned. The results were similar to clinical practice and also with several qualitative reviews, i.e. low efficiency. It was observed few studies of good quality, low number randomized clinical trials, and quantitative systematic review, as well. Thus, (HS) has not yet been mapped into the Evidence-Based paradigm and justifies the low assertiveness of therapeutic modalities conventionally instituted to date, as most of them are still structured empirically. Under this circumstance, and due experience and achieviments with these patients at the Instituto da Pele/Departamento de Dermatologia da Escola Paulista de Medicina da Universidade Federal de São Paulo/UNIFESP/Brazil (Monson 2019) [1], was decided to expand spectrum the research, and to add Oral and Systemic Health and Women’s Health, simultaneously to the conventionally studied biopsycho-social parameters. The results were not surprising and revealed the importance of expanding scientific research on HS. As implications for practice, we sought to qualitatively map knowledge to help organize a comprehensive minimum protocol for HS care beyond the conventionally adopted parameters, and include ways of measuring the quality levels of oral health and women’s health with aimed at the quality of life of these patients. Thus, a more realistic and assertive management could be given to the target population, as well as the adoption of complementary therapeutic modalities (according to WHO parameters), and applied in a co-intervention regime, to control these new sets of comorbidities that have been considered by the present study with the objective of increasing the levels of efficacy, effectiveness and safety by Good Clinical Practices. Even though we still do not have the methodological conditions to establish Guidelines for HS, we at least strive to make care for these patients increasingly humanized and inclusive

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Section: Hidradenitis Suppurativa and Mental Health (Psychiatric Dise...mentioning

confidence: 99%

Qualitative Systematic Review on the Bio-Psycho-Socioeconomic Impact of Hidradenitis Suppurativa/Acne Inversa

Augusto,

Monica,

Giulia

et al. 2024

J Surgery

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“…Patients with HS are also at significantly higher risk of depression (5.9% vs 3.5% in controls) or anxiety disorders (3.9% vs 22.4% in controls), which are also significantly after controlling for age and sex ( 15 ). In general, 29.4% of patients with HS show additional mental health symptoms, mainly depression, but also, for example, nicotine and alcohol disorders ( 16 ). In a qualitative study with affected people, a high degree of stigmatization and a resulting tabooing of the disease were found ( 5 ).…”

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confidence: 99%

Measuring Quality of Life in Hidradenitis Suppurativa: Development and Validation of a Disease-specific Patient-reported Outcome Measure for Practice and Research

et al. 2023

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Hidradenitis suppurativa is a chronic disease that disrupts patients’ physical and psychological well-being. A disease-specific measure was developed and validated for assessing health-related quality of life in hidradenitis suppurativa. After qualitative item development, the quality of life in hidradenitis suppurativa instrument was tested in 101 patients, applying convergent measures and a usability questionnaire. Descriptive and validation-specific analyses were conducted. There was no ceiling, but moderate floor effects (scores between 0 and 3.13 on a scale of 0–4). Few missing values were observed (21 of 23 items < 5%). Internal consistency was satisfying: 2 subscales with 6 and 16 items were identified (Cronbach’s alpha=0.95 and 0.88). The quality of life in hidradenitis suppurativa instrument correlated significantly with all convergent criteria (including change in convergent patient-reported outcomes; p < 0.05) except for Hurley stage (p = 0.490). In conclusion, the quality of life in hidradenitis suppurativa questionnaire is an internally consistent, valid, responsive, and usable instrument to assess quality of life in patients with hidradenitis suppurativa.

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Psychiatrische Komorbidität bei Hidradenitis suppurativa/Acne inversa

Cited by 2 publications

References 53 publications

Qualitative Systematic Review on the Bio-Psycho-Socioeconomic Impact of Hidradenitis Suppurativa/Acne Inversa

Qualitative Systematic Review on the Bio-Psycho-Socioeconomic Impact of Hidradenitis Suppurativa/Acne Inversa

Measuring Quality of Life in Hidradenitis Suppurativa: Development and Validation of a Disease-specific Patient-reported Outcome Measure for Practice and Research

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