Psychiatric Symptoms and Psychosocial Problems in Patients with Breast Cancer

İzci, Filiz; İlgün, Ahmet Serkan; Fındıklı, Ebru; Özmen, Vahit

doi:10.5152/tjbh.2016.3041

Cited by 77 publications

(72 citation statements)

References 83 publications

(65 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…More than one third of breast cancer patients were suffering from mild, moderate, or severe depression after cancer diagnosis and 1‐year follow‐up as well. These findings meet with the data of other surveys that a significant number of breast cancer patients has 2 to 3 times elevated anxiety and depression . The prevalence of depression in different investigations varies from 9 till 56%, and no significant effect of time on depression was found …”

Section: Discussionsupporting

confidence: 90%

“…Breast cancer is the second most common cancer in the world and the most frequent cancer among women . This disease is one of the most stressful events in someone's life, what can trigger a depression . In investigations made worldwide tendency was observed, that older, not employed, low educated and single patients are more prone to depression .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The risk factors for depression in Lithuanian breast cancer patients

et al. 2018

View full text Add to dashboard Cite

KEYWORDSbreast cancer, depression, delivery of diagnosis, psychocial, risk factors, support 1 | BACKGROUND Breast cancer is the second most common cancer in the world and the most frequent cancer among women. 1 This disease is one of the most stressful events in someone's life, what can trigger a depression. 2 In investigations made worldwide tendency was observed, that older, not employed, low educated and single patients are more prone to depression. [3][4][5][6] Lithuania remains a country where depression in cancer patients is under studied. Taking into account that the suicidal rate of the general population of Lithuania is one of the biggest in Europe since 1993, 7 it is very important to investigate the risk factors for depression. Lithuania is a country in which many economic, political, and social changes have occurred during the last two decades. We had a hypothesis that risk factors of depression in Lithuanian breast cancer patients will differ from other European non post-soviet countries because of economic level and social-cultural features. 8 The main aims of this study were to evaluate prevalence and risk for depression in Lithuanian women diagnosed with breast cancer, and to identify the influence of social, demographic, psychological, and clinical factors on the depression. 2 | METHODS 2.1 | Design and data collection The questionnaire survey was performed in the National Cancer Institute between 2012 and 2014. Participants were newly diagnosed breast cancer patients, age 18 to 80 years with T1-3N0-3M0 stage breast cancer. Patients completed questionnaires before beginning cancer treatment and at one-year follow-up. Completed questionnaires included: The Beck Depression Inventory Second Edition (BDI-II) 9 ; Vrana &Lauterbach Traumatic Events Scale-Civilian version (TEQ) 10 ; a questionnaire on patients' satisfaction about the communication of the diagnosis, and necessity of psychological support. | Statistical analysisDescriptive statistics were used to characterize the sample. Categorical variables were expressed as absolute and relative frequencies.Mann-Whitney U was used for between-group comparisons of BDI-II scores and Pearson's chi-square test for categorical variables. Categorical variables were compared using Pearson's chi-square test. The odds ratios (OR) and 95% confidence intervals (95% CI) for depression and risk variables were estimated using multiple logistic regression.The BDI-II cut-off of ≥13 score was used to dichotomize patients into cases and non-cases. Unvariate logistic regression was conducted to explore the unadjusted association between variables and outcome.Likelihood ratio test was used for models fit. Summary measures of goodness of fit (likelihood ratio chi-square and Hosmer and Lemeshow's goodness-of-fit test) were conducted for assessing fit of the models. Receiver operating characteristics curve was used to assess discrimination power of the model. For assessing changes of prevalence of depression symptoms over time, McNemar's chi-square

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

The risk factors for depression in Lithuanian breast cancer patients

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Here are some factors that my influence the development of depression in these patients: Socioeconomic status, social support, recent losses, and the patient's perception of the disease. Besides, the psychological impact of the disease itself is already an important factor for the development of psychiatric comorbidities [3].…”

Section: Tamoxifen Metabolismmentioning

confidence: 99%

“…Breast cancer is responsible for the largest number of diagnoses and deaths in Latin America [2]. Epidemiological data collected in 2002 indicated that breast cancer was responsible for approximately 33% of all the neoplasms, and for 20% of deaths caused by cancer [3].…”

Section: Introductionmentioning

confidence: 99%

Treatment of Depression in Patients under Breast Cancer Therapy: Antidepressant-Tamoxifen Drug Interactions

Aguiar¹,

Aguiar²,

Rocha³

2017

J Drug Metab Toxicol

View full text Add to dashboard Cite

The hormone therapy with tamoxifen is used in patients with breast cancer. The tamoxifen mechanism of action is based on the antagonist action of selective estrogen receptors. Depression and anxiety are psychiatric disorders which frequently coexist in patients with breast cancer. In the last decades, there has been an increase in the use of antidepressants. This literature review aims to provide a general view of pharmacokinetic knowledge of drug interactions between tamoxifen and antidepressants. Since tamoxifen is metabolized by CYP2D6, the use of antidepressants that are inhibitors of this is enzyme, such as paroxetine, fluoxetine and bupropion must be avoided. Based on cytochrome p450 drug interactions, it can be concluded that the use of citalopram, escitalopram, desvenlafaxine and venlafaxine are safe and effective treatment unlikely to alter tamoxifen efficacy.

show abstract

“…In this context, depression and anxiety disorders emerge in most patients. Studies have shown that depression and anxiety are the most common problems that appeared in cancer patients (12,13). Severe depression often causes the patients to spend the rest of their lives waiting for death (14).…”

Section: Contextmentioning

confidence: 99%

The Single Item Burnout Measure is a Psychometrically Sound Screening Tool for Occupational Burnout

Hansen

Pit

2016

Health Scope

View full text Add to dashboard Cite

Context: Depression is common among breast cancer (BC) patients. Several studies have evaluated the prevalence of depression among BC patients in Iran. Hence, in order to have more in-depth knowledge regarding its prevalence, all available studies were systematically reviewed and their data were analyzed using a meta-analysis. Evidence Acquisition: A systematic search was conducted to find all published studies on the prevalence of depression in BC patients in the international databases (Medline/PubMed, Scopus, Embase, Google Scholar, and Web of Sciences), and Iranian databases (Scientific Information Database, MagIran, IranMedex, and IranDoc) until February 2016. This systematic review was done according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. Results: In total, nine eligible papers (out of 240) were entered into the analysis. The overall prevalence of depression in BC patients was 44% (95% CI: 35%-52%). The results of Cochran's test showed the heterogeneity of the studies (Q = 1678.2, df = 8, I 2 = 89.4%, P < 0.001). Conclusions: BC patients are at risk of depression; hence, its detection is of utmost importance in clinical practice.

show abstract

Psychiatric Symptoms and Psychosocial Problems in Patients with Breast Cancer

Cited by 77 publications

References 83 publications

The risk factors for depression in Lithuanian breast cancer patients

The risk factors for depression in Lithuanian breast cancer patients

Treatment of Depression in Patients under Breast Cancer Therapy: Antidepressant-Tamoxifen Drug Interactions

The Single Item Burnout Measure is a Psychometrically Sound Screening Tool for Occupational Burnout

Contact Info

Product

Resources

About