Psychiatric Symptoms and Health-Related Quality of Life in Children and Adolescents with Psoriasis

Abstract

Information about the relationship between psoriasis and psychiatric morbidity and quality of life in children and adolescents is limited. We aimed to examine the symptoms of depression and anxiety and health-related quality of life levels in children and adolescents with psoriasis. Forty-eight outpatients with psoriasis aged 8 to 18 years are included in this study. Child Depression Inventory (CDI), State-Trait Anxiety Inventories for Children (STAI-C) and Pediatric Quality of Life Inventory Parent and Child Versions (PedQL-P and C) were applied to both patient and control groups. Psoriasis symptom severity was measured by the Psoriasis Area Severity Index (PASI). Both study and control groups were divided into two age groups, child (8-12 yrs) and adolescent (13-18 yrs), to exclude the effect of puberty on psychological condition. The mean CDI score was higher, and PedQL-C psychosocial and total scores were lower in the children compared with controls. Duration of psoriasis had an increasing effect on physical-health and total scores of PedQL-C in the child group and all PedQL-C scores in the entire sample. Psoriasis severity showed a negative correlation with psychosocial and total scores of PedQL-P in the adolescent group and PedQL-P physical-health scores in the entire sample. Psoriasis is related to depression and impaired quality of life in children. The depressive symptoms in children with psoriasis should not be overlooked and psychiatric assessment of these children should be provided.

Awareness of Risk Factors for Skin Infections and its Impact on Quality of Life among Adults in a Malaysian City: A Cross-Sectional Study

“…These findings are similar to those of previous studies undertaken in other countries using various setups and sample sizes [23][24][25]. The effect on QoL of embarrassment and self-consciousness resulting from skin infection was also in line with other studies performed in central Saudi Arabia, in which the location of lesions caused by skin infection created a major psychological impairment in individual identity development [26,27]. Furthermore, the messiness and time-constraints imposed by the topical application of treatments for skin infection caused discomfort and annoyance [28].…”

Association of Pediatric Psoriasis Severity With Excess and Central Adiposity

“…54, 55 A recent prospective cohort study of 892 affected adult women found that increased adiposity preceded the occurrence of new onset psoriasis 21 ; we are currently addressing if increased adiposity precedes psoriasis onset in children.…”

Systematic Review of Health-Related Quality of Life in Adolescents with Psoriasis

“…This is particularly important since depressive episodes at a young age increase the risk of subsequent recurrences and long-term psychiatric disorders [20] . Bilgic et al [21] performed a casecontrol study of 48 psoriatic patients and healthy controls aged 8-18 years and found no differences in depression and anxiety in the adolescent group (13-18 years old). This unexpected finding may be explained by a small sample size (n = 26) in combination with the fact that patients had only mild psoriasis (average Psoriasis Area and Severity Index, PASI, of 9.75 ± 10.52).…”