Psychiatric Outcomes of Childhood Maltreatment: A Retrospective Chart Review from a Children’s Psychiatric Inpatient Program

Cancilliere, Mary Kathryn; Kavanaugh, Brian C.; Bodzy, Mary; Holler, Karen A.

doi:10.1007/s10578-021-01209-3

Cited by 4 publications

(2 citation statements)

References 55 publications

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“…There is considerable overlap between the most common mental health outcomes associated with sexual abuse and those associated with physical abuse, although the relationship between sexual abuse and increased susceptibility to PTSD and borderline personality disorder seems especially strong ( de Aquino Ferreira et al, 2018 ; Hailes et al, 2019 ; Breuer et al, 2020 ; Cancilliere et al, 2021 ). In addition, studies suggest that sexual abuse leads to increased dissociative symptoms ( Tschoeke et al, 2021 ) and non-suicidal self-injury and suicidal ideation, but not completion ( Mullen et al, 1994 ; de Aquino Ferreira et al, 2018 ).…”

Section: Sexual Abusementioning

confidence: 99%

Early Life Adversity and Neuropsychiatric Disease: Differential Outcomes and Translational Relevance of Rodent Models

Waters

Gould

2022

Front. Syst. Neurosci.

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It is now well-established that early life adversity (ELA) predisposes individuals to develop several neuropsychiatric conditions, including anxiety disorders, and major depressive disorder. However, ELA is a very broad term, encompassing multiple types of negative childhood experiences, including physical, sexual and emotional abuse, physical and emotional neglect, as well as trauma associated with chronic illness, family separation, natural disasters, accidents, and witnessing a violent crime. Emerging literature suggests that in humans, different types of adverse experiences are more or less likely to produce susceptibilities to certain conditions that involve affective dysfunction. To investigate the driving mechanisms underlying the connection between experience and subsequent disease, neuroscientists have developed several rodent models of ELA, including pain exposure, maternal deprivation, and limited resources. These studies have also shown that different types of ELA paradigms produce different but somewhat overlapping behavioral phenotypes. In this review, we first investigate the types of ELA that may be driving different neuropsychiatric outcomes and brain changes in humans. We next evaluate whether rodent models of ELA can provide translationally relevant information regarding links between specific types of experience and changes in neural circuits underlying dysfunction.

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Section: Sexual Abusementioning

confidence: 99%

Early Life Adversity and Neuropsychiatric Disease: Differential Outcomes and Translational Relevance of Rodent Models

Waters

Gould

2022

Front. Syst. Neurosci.

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“…障碍的追踪研究发现, PTSD 与抑郁、物质滥用、犯罪、自杀等不良健康结果高度相关 (Cancilliere et al, 2021;Jensen et al, 2014Jensen et al, , 2019, 其负面影响可以持续到成年期 , 甚至具有代际传递效应 (Yehuda et al, 2001) 预测分类 (Bedi et al, 2015;Mueller et al, 2010;Zandvakili et al, 2019) Saxe et al, 2017), 近年来为优化机器学习效果, 逐渐尝试非监督机器学习、深度学习等新方法 (Schultebraucks, Yadav, et al, 2020)。…”

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Application of machine learning in prognosis and trajectory of post-traumatic stress disorder in children

LIU¹,

CHEN²,

Guo³

2022

Adv Psychol Sci

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Post-traumatic stress disorder (PTSD) could have negative effects on the development of children, and its impact can even last into adulthood. However, the traditional diagnostic methods are difficult to quickly, objectively and accurately identify and diagnose PTSD in children. Machine learning, as an emerging method to deal with a large number of variables and data, has gradually been applied to the research of early prediction, recognition and auxiliary diagnosis of PTSD in children. Machine learning, with its advantages in performance and algorithm, can be applied to the recognition and prognosis of PTSD in children. Compared with self-reported diagnosis, the process of identifying and diagnosing PTSD in children through machine learning has unique advantages of high efficiency, objective accuracy and resource saving. However, machine learning has limitations in terms of hardware cost, algorithm selection and prediction accuracy. In the future, researchers need to further improve the accuracy of machine learning diagnosis and children's PTSD recognition, and explore more combinations of machine learning and traditional diagnosis methods.

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Adverse childhood experiences exacerbate peripheral symptoms of autism spectrum disorder in adults

Okumura,

Takeda,

Komori

et al. 2024

Psychiatry Clin Neurosci

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AimAdverse childhood experiences are potentially traumatic events with long‐lasting effects on the health and well‐being of patients with autism spectrum disorder (ASD). It is important to clarify which types of long‐lasting autism‐related symptoms are influenced by childhood experiences to design future intervention studies. However, few studies have examined the association between childhood experiences and autistic symptoms in large samples of adults with ASD and individuals with typical development (TD). In this study, we evaluate the effects of adverse childhood experiences on multiple ASD phenotypes among both individuals with ASD and those with TD.MethodWe combined questionnaire evaluations; Childhood Abuse and Trauma Scale, the Japanese version of the Autism‐Spectrum Quotient, Conners' Adult ADHD Rating Scale, the Japanese version of the Impact of Event Scale‐Revised, and the Japanese version of the Adolescent/Adult Sensory Profile.ResultsIndividuals with ASD and those with TD (n = 205 and 104, respectively) were included. There were significant correlations between the extent of adverse childhood experiences and severity of attention‐deficit/hyperactivity disorder symptoms, posttraumatic stress disorder symptoms, and hypersensitivity in both participants with ASD and those with TD. By contrast, ASD core symptoms showed no significant correlation with adverse childhood experiences in either group. These results remained consistent after adjusting for age, sex, and the estimated intelligence quotient.ConclusionThese findings suggest the need for a detailed disentanglement of ASD‐related core and peripheral symptoms of adverse childhood experiences, which may help to appropriately set outcomes for future early interventions for the childhood experiences of individuals with ASD.

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Psychiatric Outcomes of Childhood Maltreatment: A Retrospective Chart Review from a Children’s Psychiatric Inpatient Program

Cited by 4 publications

References 55 publications

Early Life Adversity and Neuropsychiatric Disease: Differential Outcomes and Translational Relevance of Rodent Models

Early Life Adversity and Neuropsychiatric Disease: Differential Outcomes and Translational Relevance of Rodent Models

Application of machine learning in prognosis and trajectory of post-traumatic stress disorder in children

Adverse childhood experiences exacerbate peripheral symptoms of autism spectrum disorder in adults

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