Psychiatric Manifestations of Mercury Poisoning

A Comparison of Urinary Mercury between Children with Autism Spectrum Disorders and Control Children

“…In Iraq in the 1970s, over 450 people died and over 5000 suffered poisoning following the use of methylmercury fungicide to treat grain [14], [15] and in Japan, industrial waste containing mercury, poisoned over 2000 people [4]. There have been several reviews examining mercury poisoning from follow up studies in Japan, Iraq, Peru, the Philippines, the Faroe Islands and the Seychelles [12], [13], [16], [17].…”

Efectos neurotóxicos del timerosal, a dosis de vacuna, sobre el encéfalo y el desarrollo en hámsteres de 7 días de nacidos

“…James y col. ( 72 ) han mostrado que el timerosal induce estrés oxidativo y la apoptosis de neuronas, astrocitos y células T humanas, activando vías metabólicas mitocondriales de muerte celular. Lo anterior explica las alteraciones observadas a nivel de la estructura neuronal, que traería como consecuencia una disminución en la población de neuronas, lo cual se asocia en la clínica a trastornos en el desarrollo psicomotor, retardo del lenguaje, problemas de comportamiento, pérdida de la visión, audición, convulsiones, autismo, etc ( [94][95][96] ). Recientemente, diversas investigaciones han demostrado también que el timerosal es capaz de dañar severamente la metilación, una ruta metabólica crítica en la habilidad de los factores de crecimiento para promover el desarrollo neurológico normal ( 72,[97][98][99] ).…”

Mercury Exposure and Endothelial Dysfunction

“…[17][18][19][20][21][22][23][24][25][26][27][28][29][30][31] Numerous population studies have reported tachycardia, high blood pressure (BP), decreased heart rate variability (HRV), increase in the risk of stroke, and increased risk of total cardiovascular mortality. 17,[19][20][21][22][23][24][25] In a native population of Quebec (Canada), organic mercury exposure has been associated with increased resting HR but with no significant association with BP. 26 In a study conducted on 274 schoolchildren, an increased level of mercury in urine has been associated with elevated cholesterol level, which is a known risk factor for myocardial infarction, coronary disease, and CVD.…”