Psychiatric factors do not affect recurrence risk of hyperemesis gravidarum

Magtira, Aromalyn; Schoenberg, Frederic Paik; MacGibbon, Kimber; Tabsh, Khalil; Fejzo, Marlena S.

doi:10.1111/jog.12592

Cited by 18 publications

(25 citation statements)

References 16 publications

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“…In keeping with the Christodoulou‐Smith et al. study, up to 18% of women with HG fulfilled the full criteria for PTSD . There did not appear to be an increased risk of HG recurrence in those women fulfilling the full stress criteria.…”

Section: Resultssupporting

confidence: 77%

“…A further study by Magtira et al looked at recurrence rates of HG in women who reported symptoms of PTSD following their initial pregnancy affected by HG and so indirectly reported on the rate of PTSD in women suffering HG. 35 In keeping with the Christodoulou-Smith et al study, up to 18% of women with HG fulfilled the full criteria for PTSD. 35 There did not appear to be an increased risk of HG recurrence in those women fulfilling the full stress criteria.…”

Section: Total (95% Ci)supporting

confidence: 62%

“…A further study by Magtira et al. looked at recurrence rates of HG in women who reported symptoms of PTSD following their initial pregnancy affected by HG and so indirectly reported on the rate of PTSD in women suffering HG . In keeping with the Christodoulou‐Smith et al.…”

Section: Resultsmentioning

confidence: 90%

See 2 more Smart Citations

Psychological morbidity associated with hyperemesis gravidarum: a systematic review and meta‐analysis

Mitchell-Jones

Gallos

Farren

et al. 2016

BJOG

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Background Psychological illness occurring in association with hyperemesis gravidarum (HG) has been widely reported.Objective To determine if there is a higher incidence of psychological morbidity in women with HG compared with women without significant nausea and vomiting in pregnancy.Search strategy PubMed, MEDLINE, Embase and PsychINFO were searched up to September 2015.Selection criteria Articles referring to psychological morbidity in relation to HG. For meta-analysis case-control studies using numerical scales to compare psychological symptoms.Data collection and analysis Articles were independently assessed for inclusion by two reviewers and methodology was appraised using the Newcastle Ottawa Scale. Comparison was made using the standard mean difference (SMD) in symptom scale scores.Main results In all, 59 articles were included in the systematic review, 12 of these were used in the meta-analysis. Meta-analysis of depression scale scores demonstrated a very large effect with statistically significantly higher depression scale scores in women with HG (SMD 1.22; 95% CI 0.80-1.64; P ≤ 0.01) compared with controls. Meta-analysis of anxiety scores demonstrated a large effect with statistically significantly higher anxiety disorder scale scores in women with HG (SMD 0.86; 95% CI 0.53-1.19; P ≤ 0.01). In both analyses significant heterogeneity was identified (depression and HG I 2 = 94%, P ≤ 0.01; anxiety and HG I 2 = 84%, P = 0.02).Conclusions Our systematic review and meta-analysis have shown a significantly increased frequency of depression and anxiety in women with HG. The findings should prompt service development for women with HG that includes provision of psychological care and support.Keywords Anxiety, depression, hyperemesis gravidarum, pregnancy, sickness, vomiting.Tweetable abstract Meta-analysis demonstrates an increase in #PsychologicalMorbidity in women with #HyperemesisGravidarum Please cite this paper as: Mitchell-Jones N, Gallos I, Farren J, Tobias A, Bottomley C, Bourne T. Psychological morbidity associated with hyperemesis gravidarum: a systematic review and meta-analysis. BJOG 2017;124:20-30.

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Section: Resultssupporting

confidence: 77%

Section: Total (95% Ci)supporting

confidence: 62%

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Psychological morbidity associated with hyperemesis gravidarum: a systematic review and meta‐analysis

Mitchell-Jones

Gallos

Farren

et al. 2016

BJOG

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“…On the other hand, Magtira et al (2014) found no statistically significant differences in the prevalence of psychiatric conditions prior to the first pregnancy when comparing 84 women with recurrence of HG with 34 women with no recurrence. The authors predicted that if psychiatric symptoms positively correlate with HG, then psychiatric symptoms would correlate positively with recurrence risk.…”

Section: Discussionmentioning

confidence: 95%

History of depression and risk of hyperemesis gravidarum: a population-based cohort study

Kjeldgaard

Eberhard‐Gran

Benth

et al. 2017

Arch Womens Ment Health

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Hyperemesis gravidarum (HG) is a pregnancy condition characterised by debilitating nausea and vomiting. HG has been associated with depression during pregnancy but the direction of the association remains unclear. The aim of this study was to assess whether previous depression is associated with HG. This is a population-based pregnancy cohort study using data from The Norwegian Mother and Child Cohort Study. The study reviewed 731 pregnancies with HG and 81,055 pregnancies without. Logistic regression analyses were performed to examine the association between a lifetime history of depression and hyperemesis gravidarum. Odds ratios were adjusted for symptoms of current depression, maternal age, parity, body mass index, smoking, sex of the child, education and pelvic girdle pain. A lifetime history of depression was associated with higher odds for hyperemesis gravidarum (aOR = 1.49, 95% CI (1.23; 1.79)). Two thirds of women with hyperemesis gravidarum had neither a history of depression nor symptoms of current depression, and 1.2% of women with a history of depression developed HG. A lifetime history of depression increased the risk of HG. However, given the fact that only 1.2% of women with a history of depression developed HG and that the majority of women with HG had no symptoms of depression, depression does not seem to be a main driver in the aetiology of HG.

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“…Lingam and McCluskey noted development or worsening of eating disorders during pregnancy is associated with hyperemesis gravidarum . Of note, psychiatric factors such as anxiety and depression did not increase the risk of recurrence of hyperemesis gravidarum in a second pregnancy . The etiologies behind the development of hyperemesis gravidarum are poorly understood and it is unclear how psychological factors play a role.…”

Section: Resultsmentioning

confidence: 99%

Obstetric and gynecologic problems associated with eating disorders

Kimmel

Ferguson

Zerwas

et al. 2015

Intl J Eating Disorders

111

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Objective This article summarizes the literature on obstetric and gynecologic complications associated with eating disorders. Method We performed a comprehensive search of the current literature on obstetric and gynecologic complications associated with eating disorders using PubMed. More recent randomized-controlled trials and larger data sets received priority. We also chose those that we felt would be the most relevant to providers. Results Common obstetric and gynecologic complications for women with eating disorders include infertility, unplanned pregnancy, miscarriage, poor nutrition during pregnancy, having a baby with small head circumference, postpartum depression and anxiety, sexual dysfunction and complications in the treatment for gynecologic cancers. There are also unique associations by eating disorder diagnosis, such as earlier cessation of breastfeeding in anorexia nervosa; increased polycystic ovarian syndrome in bulimia nervosa; and complications of obesity as a result of binge eating disorder. Discussion We focus on possible biological and psychosocial factors underpinning risk for poor obstetric and gynecological outcomes in eating disorders. Understanding these factors may improve both our understanding of the reproductive needs of women with eating disorders and their medical outcomes. We also highlight the importance of building multidisciplinary teams to provide comprehensive care to women with eating disorders during the reproductive years.

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Psychiatric factors do not affect recurrence risk of hyperemesis gravidarum

Cited by 18 publications

References 16 publications

Psychological morbidity associated with hyperemesis gravidarum: a systematic review and meta‐analysis

Psychological morbidity associated with hyperemesis gravidarum: a systematic review and meta‐analysis

History of depression and risk of hyperemesis gravidarum: a population-based cohort study

Obstetric and gynecologic problems associated with eating disorders

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