It is believed that an isolated pulsar loses its rotational energy mainly through a relativistic wind consisting of electrons, positrons and possibly Poynting flux 1-3 . As it expands, this wind may eventually be terminated by a shock, where particles can be accelerated to energies of X-ray synchrotron emission, and a pulsar wind nebula (PWN) is usually detectable surrounding a young energetic pulsar 1-3 . However, the nature and/or energetics of these physical processes remain very uncertain, largely because they typically cannot be studied in a timeresolved fashion. Here we show that the X-ray PWN around the young pulsar PSR B0540-69 brightens gradually up to 32±8% over the mean previous flux, after a sudden spin-down rate (ν) transition (SRT) by ∼ 36% in December 2011, which has very different properties from a traditional pulsar glitch 4 . No evidence is seen for any change in the pulsed X-ray emission. We conclude that the SRT results from a sudden change in the pulsar magnetosphere that increases the pulsar wind power and hence the PWN X-ray emission. The X-ray light curve of the PWN suggests a mean life time of the particles of 397 ± 374 days, corresponding to a magnetic field strength of 0.78 +4.50 −0.28 mG in the PWN.