Psoriatic Arthritis Mutilans: Case Series and Literature Review

Psoriatic Arthritis Mutilans: Characteristics and Natural Radiographic History

“…We therefore propose that PAM can be monoarticular, although it is more frequently polyarticular and the notion is supported by data from other studies 1,12,13,18 . Review of these 7 cases in our outpatient clinic demonstrated clinical evidence of PAM, with shortened telescopic digits.…”

Psoriatic Arthritis Mutilans: Clinical and Radiographic Criteria. A Systematic Review

“…The presence of nail lesions was reported in 47% of patients with PAM in 1 case series 21 . Patients with PAM had 1 33,37 or more 22,24,25,28,34,40,45,47,52,56,60,63,67,69 affected joints involving any of the interphalangeal, metacarpophalangeal, or metatarsophalangeal joints. PAM was reported to occur within a few months 25,37 and up to several years 33,45 after PsA onset.…”

“…,49,50,51,52,53,54,56,[59][60][61][62][63][64][65][66][67][68][69]70,71,72,73 . Based on reported data, 86/166Personal non-commercial use only.…”

Applying precision medicine to unmet clinical needs in psoriatic disease

“…However, PAM is difficult to identify and study, owing to its rarity and relatively short period of joint destruction followed by a protracted inactive phase [9]. Studies of PAM to date have been crosssectional [29,30,31,32,33,34,35,36,37,38], with fewer than 200 cases described in total and only one published longitudinal study [9]. Furthermore, no studies of pathological specimens from patients with PAM have been published; thus, the pathological differences between bony erosion, osteolysis and osteoproliferation in PAM are poorly understood.…”