Psoriasis‐like dermoscopic pattern of clear cell acanthoma

Abstract

The vascular psoriasis-like dermoscopic findings seem to be a clue for CCA and provide evidence of an inflammatory process for CCA formation.

Dermoscopy in General Dermatology

“…From 1955 to January 2005, we found 61 dermoscopy articles reporting a variety of different indications in the context of NPSD [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61]. Preferentially we did not include dermoscopy articles in which the differential diagnosis to pigmented skin tumors was discussed.…”

“…A practical example explaining the application of the dermoscopic algorithm to differentiate NPSD is the following: amelanotic melanoma [3,4,5,6,7] and psoriasis [7,8,9,10,11,12,13] might reveal both dotted vessels by dermoscopy. However, the clinical appearance of a single lesion in the former and the typical location of multiple lesions in the latter, allow distinguishing this highly malignant skin tumor from the harmless plaques of psoriasis (step 1).…”

Post Term Gebeliklerde Doğum İndüksiyonu Öncesinde Lokal İsosorbid Mononitrat Uygulamasının Servikal Olgunlaşma ve Doğum Eylemi Üzerine Etkisi

“…CCA and psoriasis have close dermatoscopic resemblance consisting in homogenous, symmetrically or bunch-like arranged pinpoint capillaries (2,3). The significant features identified for psoriasis are a homogenous vascular pattern, red dots, and light-red background, yielding a diagnostic probability of 99% if all 3 features are present (2,3). The distribution of the dotted vessels in psoriasis is not so reticular, nor even annular as seen in CCA.…”

Multiple eruptive clear cell acanthoma

“…There is an association with other skin diseases: xerosis, hyttiosis and seborrhoic keratosis. 8 The most distinctive histopathologic features of CCA are well-demarcated: acanthotic epidermis composed of glycogen-rich clear cells that can be revealed by positive PAS (Periodic acid-Schiff) staining and removal of the staining after diastase digestion. The epidermis is frequently infiltrated by abundant numbers of neutrophils, which may form microabscesses in the parakeratotic stratum corneum.…”

“…Dermoscopically dotted or globular vessels, similar to those seen in psoriasis and Bowen disease, are found. 7,8 Thus, in lesions with this pattern, located on an extremity, unequivocal differentiation from Bowen's disease may be difficult based on clinical and dermoscopic features alone, necessitating biopsy for histological examination. Reflectance Confocal Microscopy has been used for the evaluation of non-melanocytic neoplasms, showing microscopic findings similar to optical histology.…”