Psoriasis: Epidemiology, Clinical and Histological Features, Triggering Factors, Assessment of Severity and Psychosocial Aspects

Comparison of PASI and DLQI among Out-Patients Andin-Patients with Psoriasis in a Tertiary Care Centre

“…Psoriasis is a persistent, disfiguring and stigmatizing disease, that leads to psychological and emotional impact in the patients, that needs to be substantiated. 7 Psoriatic patients, not only have severe psychological disability, but they also have substantial impairment of health related quality of life. It is thought that HRQOL is more resolute by how an individual mentally handles the disease than by the amount of skin affected.…”

“…Psoriasis is bimodal in onset, with two peaks at 16-22 and other at 57-60 years of age. 7 The mean age of onset of psoriasis vulgaris is 33 years. 11 But Dogra S, Savita Y et al, inferred that in India most of the patients are in their third or fourth decade at the time of presentation.…”

“…It appears that, there is not always a strong correlation between the HRQOL and the severity of the disease, as defined by PASI. 7 Thus it is revealed that the clinical severity had positive correlation with psychiatric morbidity and quality of life. The patients from inpatient department showed that severe depression had moderate PASI score with high DLQI, so this revealed the fact that distortion of quality of life of psoriatic patients not only involves the clinical severity, but other factors like duration of the disease, disease chronicity, expense of treatment, moral support also influence the quality of life.…”

Perbandingan Kadar Kortisol Dalam Serum Pasien Psoriasis Vulgaris Dengan Bukan Pasien Psoriasis Vulgaris

“…Tidak ada perbedaan prevalensi terhadap jenis kelamin. 4,5 Etiopatogenesis penyakit ini kompleks, melibatkan faktor genetik, imunologik, dan lingkungan. Sebagian besar penelitian yang telah dilakukan fokus pada peran sitokin dan sel imun.…”

“…11,12 Meskipun demikian, sebagian besar literatur menyatakan bahwa psoriasis mempengaruhi kedua jenis kelamin secara seimbang. 4,5 Kejadian psoriasis vulgaris pada subyek kasus penelitian ini memiliki distribusi terbanyak pada kelompok usia 41-50 tahun (40%), dan terendah pada kelompok usia di atas 60 tahun (5%). Hasil yang mirip didapatkan dari penelitian yang dilakukan oleh Wardhana, di mana pasien psoriasis terbanyak terdapat pada kelompok usia 30-50 tahun (53%), dan terendah pada kelompok usia di atas 50 tahun (18%).…”