Psoralen Isolated from the Roots of Dorstenia psilurus Welw. Modulate Th1/Th2 Cytokines and Inflammatory Enzymes in LPS‐Stimulated RAW 264.7 Macrophages
Adamu Imam Isa,
Hugues Fouotsa,
Osama A. Mohammed
et al.
Abstract:Dorstenia psilurus is a widely used plant spice in traditional African medicine to treat pain‐related conditions. However, the anti‐inflammatory mechanisms underlying this activity and the main active ingredients of D. psilurus have not yet been fully characterized. This study aimed to isolate and identify the main active anti‐inflammatory constituents of the D. psilurus extract and to investigate the underlying anti‐inflammatory mechanisms in murine macrophages. Chromatographic techniques and spectroscopic da… Show more
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