“…Widespread hand dermatitis on initial examination was found to be the greatest factor for a poor long-term prognosis in another study [Meding et al 2005]. In addition, many skin disorders, including contact dermatitis, have been shown to have a significant impact on quality of life [Kadyk et al 2003;Cvetkovski et al 2005;Fowler et al 2006;Lan et al 2008]. …”