Psilocybin containing mushrooms: a rapidly developing biotechnology industry in the psychiatry, biomedical and nutraceutical fields

Strauss, Dominique; Ghosh, Soumya; Murray, Zurika; Gryzenhout, Marieka

doi:10.1007/s13205-022-03355-4

Cited by 4 publications

(7 citation statements)

References 136 publications

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“…Acutely, psilocybin causes profound dose-related alterations in perceptions, emotions and thought in humans, leading to its classification as a hallucinogen or psychedelic drug. These alterations are produced by manipulation of the serotoninergic system (Strauss et al, 2022). The effects of serotonergic hallucinogens such as psilocybin differ from psychotic experiences.…”

Section: Marie Crowementioning

confidence: 99%

Experiences of psilocybin treatment for clinical conditions: A qualitative meta‐synthesis

Crowe

Manuel

Carlyle

et al. 2023

Int J Mental Health Nurs

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There is increasing clinical interest in the use of psilocybin. There is emerging evidence of the efficacy of psilocybin for the treatment of a range of clinical conditions. Mental health nurses have a unique set of skills for caring for people who are hallucinating. To expand these skills to meet the developing clinical interest in the therapeutic use of psilocybin, it is helpful to understand the experience from the perspective of the person being treated with psilocybin. A qualitative meta-synthesis was conducted to examine how those with psilocybin described their experiences to identify whether its effects are similar across different health conditions. Ten studies were included in the review. The health conditions studied were cancer, depression, HIV, substance use disorder, smoking cessation and trauma. The synthesis of findings identified three themes that were common across the studies despite the health condition: acceptance, connection and transformation. The review provides helpful insights into how people experience psilocybin and its effects on their health condition.

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Section: Marie Crowementioning

confidence: 99%

Experiences of psilocybin treatment for clinical conditions: A qualitative meta‐synthesis

Crowe

Manuel

Carlyle

et al. 2023

Int J Mental Health Nurs

View full text Add to dashboard Cite

show abstract

“…The highest levels of psilocybin was regularly found to be in P. cyanescens fruiting bodies [ 8 , 93 , 106 ]. Furthermore, alkaloid detection studies for all of the other known related alkaloids [ 19 ] have not yet been published. Chemical methods to detect psilocybin and psilocin include gravity flow liquid chromatography, liquid chromatography-mass spectrometry, thin layer chromatography, gas chromatography, high-performance liquid chromatography, and capillary zone electrophoresis [ 37 , 57 , 93 , [98] , [99] , [100] , [101] , [102] , [103] , [104] , [105] ].…”

Section: Discussionmentioning

confidence: 99%

“…Upon legalization in several countries research into medicinal aspects are exploding with small to large pharmaceutical companies starting to invest significant resources to harness the therapeutic powers of psilocybin analogues and the fungi that produce them [ [19] , [20] , [21] ]. Whereas these compounds can be synthesized, it is the organic nature of consuming the mushrooms that naturally produce these compounds, which appeal most to the public.…”

Section: Introductionmentioning

confidence: 99%

“…A number of powerful psilocybin-producing species are also known in Panaeolus [ 22 ] with species shown to produce psilocybin, its psychoactive metabolite psilocin, and other related alkaloids [ 19 ]. Hence species of Panaeolus, typified by Panaeolus papilionaceus [ 23 , 24 ], are known for their notable health benefits and hallucinogenic properties [ [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] ].…”

Section: Introductionmentioning

confidence: 99%

“…P. antillarum and P. cyanescens have significant antioxidant, antiviral, antibacterial and antifungal activities [ 33 , 35 ], while P. cyanescens can also be anti-inflammatory [ 36 ]. Some species that are hallucinogenic include P. s ubbalteatus, P. cyanescens and P. cambodginiensis [ 5 , 19 , 37 ].…”

Section: Introductionmentioning

confidence: 99%

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