Psidium guajava: A review of its traditional uses, phytochemistry and pharmacology

Gutierrez, Rosa Martha Pérez; Mitchell, Sylvia; Solís, Rosario Vargas

doi:10.1016/j.jep.2008.01.025

Cited by 740 publications

(538 citation statements)

References 74 publications

(91 reference statements)

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“…The Psidium guajava is well-known medicinal plant and leaves of its are widely used in the Ayurvedic system of medicine as well as in folk medicine (Gutiérrez et al 2008). Guava leaf extract is used as astringent, anodyne, febrifuge, antispasmodic, tonic to treat wounds, ulcer, cholera, diarrhoea, vomiting, nephritis, toothache, gum inflammation, etc.…”

Section: Resultsmentioning

confidence: 99%

Biogenic synthesis of silver nanoparticles using guava (Psidium guajava) leaf extract and its antibacterial activity against Pseudomonas aeruginosa

2015

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Among the various inorganic nanoparticles, silver nanoparticles have received substantial attention in the field of antimicrobial research. For safe and biocompatible use of silver nanoparticles in antimicrobial research, the different biogenic routes are developed to synthesize silver nanoparticles that do not use toxic chemicals. Among those, to synthesize silver nanoparticles, the use of plant part extract becomes an emerging field because plant part acts as reducing as well as capping agent. For large-scale production of antibacterial silver nanoparticles using plant part, the synthesis route should be very simple, rapid, cost-effective and environment friendly based on easy availability and non-toxic nature of plant, stability and antibacterial potential of biosynthesized nanoparticles. In the present study, we report a very simple, rapid, cost-effective and environment friendly route for green synthesis of silver nanoparticles using guava (Psidium guajava) leaf extract as reducing as well as capping agent. This plant has been opted for the present study for its known medicinal properties, and it is easily available in all seasons and everywhere. The biosynthesized silver nanoparticles are characterized by UV-Vis and TEM analysis. The average particle size is 40 nm in the range of 10-90 nm. The antibacterial activity of these nanoparticles against Pseudomonas aeruginosa MTCC 741 has been measured by disc diffusion method, agar cup assay and serial dilution turbidity measurement assay. The results show that green synthesized silver nanoparticles, using guava (Psidium guajava) leaf extract, have a potential to inhibit the growth of bacteria.

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Section: Resultsmentioning

confidence: 99%

Biogenic synthesis of silver nanoparticles using guava (Psidium guajava) leaf extract and its antibacterial activity against Pseudomonas aeruginosa

2015

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“…Other pharmacological activities have been described for the guava, such as an antiseptic effect, the treatment of diarrhea, dysentery, diabetes mellitus, and others (Gutiérrez, Mitchell, Solis, 2008). Also, its use is suggested among other agroindustrial products, as a food additive endowed with antimicrobial, texturizing and antioxidant activities (Ayala-Zavala et al, 2011;Ashraf et al, 2016), however, its use as a source of antioxidants for cosmetic application has so far not been studied in detail.…”

Section: Introductionmentioning

confidence: 99%

Guava: phytochemical composition of a potential source of antioxidants for cosmetic and/or dermatological applications

Chiari-Andréo

Trovatti

Marto

et al. 2017

Braz. J. Pharm. Sci.

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Guava (Psidium guajava L.) is a native fruit of the American tropics with commercial applications for its taste, flavor and aroma. Numerous pharmacological uses have been described for it, such as the antiseptic effect of its leaves, the use of the fresh fruit and tea from its leaves for the treatment of diarrhea, dysentery, diabetes mellitus, and others. However, considering its rich composition, the guava also is a potential source of antioxidants to be used in the development of new formulations for cosmetic and/or dermatological applications, the main focus of this research. Herein, we describe the study of the phytochemical composition and the antioxidant activity of a guava extract prepared with non-toxic solvents aiming its use at biological applications. High performance liquid chromatography and mass spectrometry were employed to identify the major components, while thermoanalytical measurements and hot stage microscopy were used to assess the chemical stability of guava fruit extract. The antioxidant activity was also evaluated assessing the SOD-like activity and ABTS free radical scavenger. The results show that the extract is a rich source of phenolic compounds, such as quercetin, kaempferol, schottenol, among many others. All of the components found in guava extract exhibit biological effects according to the literature data, mainly antioxidant properties. Uniterms

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“…The short-petiolate, large leaves are formed opposite each other in pairs, with prominent veins, particularly on the lower side. The blade is oval with prominent pinnate veins, 5-12 cm long (Gutierrez et al, 2008). The flowers are somewhat showy; petals whitish, up to 2 cm long and contain numerous stamens.…”

Section: Introductionmentioning

confidence: 99%

“…(family: Myrtaceae) is an important food crop and medicinal plant (Gutierrez et al, 2008). It grows in all tropical and subtropical parts of the world, and readily adapts to different climatic conditions.…”

Section: Introductionmentioning

confidence: 99%

Biphasic effect of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract on rat isolated vascular smooth muscles

Chiwororo

Ojewole

2008

J. Smooth Muscle Res.

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In this study, we examined the effects of Psidium guajava Linn. leaf aqueous extract (PGE) on isolated, spontaneously-contracting portal veins, as well as on endotheliumintact and endothelium-denuded descending thoracic aortic ring preparations of healthy, normotensive rats. Graded concentrations of PGE (0.25-4.0 mg/ml) caused concentration-dependent, initial brief but significant (P<0.05) rises of the basal tones and amplitudes of pendular, rhythmic contractions, followed by secondary pronounced, longer-lasting and significant (P<0.05-0.001) inhibitions of contractile amplitudes of the isolated portal veins. Relatively low concentrations of PGE (<1.0 mg/ml) always contracted freshly-mounted, naïve, endothelium-intact aortic ring preparations. However, relatively high concentrations of PGE (1.0-4.0 mg/ml) always produced initial brief contractions/augmentations of noradrenaline (NA, 10 -7 M)-induced contractions of endothelium-intact and endothelium-denuded aortic ring preparations, followed by secondary, pronounced relaxations of the aortic ring muscles. Moreover, relatively high concentrations of PGE (1.0-4.0 mg/kg) always relaxed NA-induced contractions of the aortic ring preparations in a concentration-related manner. The arterial-relaxing effects of PGE were more pronounced in endothelium-intact aortic rings than in endotheliumdenuded aortic ring preparations. The relaxant effects of PGE on endothelium-intact aortic rings were only partially inhibited by N G -nitro-L-arginine methyl ester (L-NAME, 100 µM), a nitric oxide synthase inhibitor, suggesting that the vasorelaxant effect of PGE on aortic rings is probably mediated via both endothelium-derived relaxing factor (EDRF)-dependent and EDRF-independent mechanisms. Taken together, the findings of this study indicate that PGE possesses a biphasic effect on rat isolated vascular smooth muscles.

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Psidium guajava: A review of its traditional uses, phytochemistry and pharmacology

Cited by 740 publications

References 74 publications

Biogenic synthesis of silver nanoparticles using guava (Psidium guajava) leaf extract and its antibacterial activity against Pseudomonas aeruginosa

Biogenic synthesis of silver nanoparticles using guava (Psidium guajava) leaf extract and its antibacterial activity against Pseudomonas aeruginosa

Guava: phytochemical composition of a potential source of antioxidants for cosmetic and/or dermatological applications

Biphasic effect of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract on rat isolated vascular smooth muscles

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