Pseudotumors

Mounajjed, Taofic; Chandan, Vishal S.

doi:10.1007/978-3-319-16089-4_1

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Subtypes Of Hepatocellular Carcinoma1

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2023

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“…The tumor cells are often associated with high-grade nuclear atypia, including enlarged, hyperchromatic nuclei and prominent nucleoli. CD34 immunostaining can be used to identify the macrotrabecular growth pattern [ 100 ]. Endothelial-specific molecule 1 (ESM1) is expressed by stromal endothelial cells in MT-HCCs and can be a reliable immunohistochemical marker of this subtype [ 64 ].…”

Section: Subtypes Of Hepatocellular Carcinomamentioning

confidence: 99%

Advances in Histological and Molecular Classification of Hepatocellular Carcinoma

Choi,

Thung

2023

Biomedicines

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Hepatocellular carcinoma (HCC) is a primary liver cancer characterized by hepatocellular differentiation. HCC is molecularly heterogeneous with a wide spectrum of histopathology. The prognosis of patients with HCC is generally poor, especially in those with advanced stages. HCC remains a diagnostic challenge for pathologists because of its morphological and phenotypic diversity. However, recent advances have enhanced our understanding of the molecular genetics and histological subtypes of HCC. Accurate diagnosis of HCC is important for patient management and prognosis. This review provides an update on HCC pathology, focusing on molecular genetics, histological subtypes, and diagnostic approaches.

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Section: Subtypes Of Hepatocellular Carcinomamentioning

confidence: 99%