Pseudotumoral reaction against oxidized cellulose (Surgicel®) in a post-COVID19 tracheostomy scar

Abstract

Cytology has demonstrated that it is capable of a specific recognition of pseudotumoral reactions induced by oxidized cellulose. This is an important observation because image studies do not allow such recognition. We report a case in a tracheostomy scar from a post-COVID19 patient that mimicked a thyroid nodule. We have found no other reports describing this complication after tracheostomy procedures. During the pandemic, the number of patients requiring invasive mechanical ventilation and tracheostomies has been high. Therefore, we believe that the phenomenon we describe is likely to be observed more frequently. The presence of a tumor lesion near a tracheostomy bed should raise the possibility of this complication and alert pathologists to the possibility of reaction to hemostatic agents.

Foreign Body Reaction Mimicking Lymph Node Metastasis is Not Rare After Lung Cancer Resection

“…Clinicians notice substantial number of cases where pathological work-up reveals foreign body reaction in patients who underwent biopsy due to hypermetabolic lympadenopathies. In the literature, this phenomenonis mostly being published through case reports where OC mimics malignancy by causing a foreign body reaction [6,7,8]. However, there is no study in the literature showing how often this condition is encountered or its differences from genuine mediastinal lymph node metastasis.…”

“…In the literature, this phenomenon is mostly being published through case reports where OC mimics malignancy by causing a foreign body reaction. [6][7][8] However, there is no study in the literature showing how often this condition is encountered or its differences from genuine mediastinal lymph node metastasis. Therefore, in our study, the frequency of foreign body reactions mimicking mediastinal lymph node metastases caused by OC and comparison of their clinicopathological features with mediastinal lymph node metastases are analyzed.…”