“…Good control of paroxysms in the third patient (who received anxiolytics treatment) speaks for diagnosis of ps-pheo. Given the proposed criteria the clinical features of the patients are suggestive of ps-pheo [5].…”
Section: Discussionmentioning
confidence: 99%
“…The panic disorder occurs in 12% of cases with hypertension [13] and shares similar symptoms with ps-pheo. However, what differentiates www.ah.viamedica.pl these conditions is that the latter is characterized by episodes of a significant increase in blood pressure in absence of any psychological triggers [5,14]. Subsequently, the patients presented in our cases do not fulfill the Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria for panic disorder [15].…”
Section: Discussionmentioning
confidence: 99%
“…PTSD is another trauma-related condition in which symptoms resemble those of ps-pheo; however, in patients with PTSD elevation of blood pressure is rarely seen [5]. Additionally, diagnosis of the PTSD requires at least 1 month of reported impairment in social, occupational, and other important areas of functioning [16].…”
Section: Discussionmentioning
confidence: 99%
“…After the episode patients usually experience fatigue [3]; blood pressure is normal or slightly increased between onsets [5]. Those symptoms usually raise suspicion of pheochromocytoma [1].…”
Section: Introductionmentioning
confidence: 99%
“…www.ah.viamedica.pl Ps-pheo is a diagnosis of exclusion as it requires further examination. Additionally, negative abdominal imaging for an adrenal tumor supports the diagnosis [5]. Differential diagnosis of ps-pheo includes panic disorder, post-traumatic stress disorder (PTSD), labile hypertension and others [5].…”
Background: Pseudopheochromocytoma is a condition that occurs more frequently than other diseases presenting with similar symptoms such as: paroxysmal hypertension, diaphoresis, pallor, palpitations. However, due to the lack of specific guidelines and awareness among physicians, it is widely underdiagnosed. Conventional antihypertensive treatment is ineffective in controlling symptoms which leads to decreased quality of life in patients affected by this disorder.
Case presentation:In our paper, we present three female patients with paroxysmal hypertension who were admitted to the Department of Endocrinology for an investigation of suspected pheochromocytoma. The biochemical findings and imaging carried out at the hospital ruled out the diagnosis of an adrenal tumor in all three of the patients. Given the proposed criteria the clinical features of the patients were suggestive of pseudopheochromocytoma. In all three cases, the anxiolytic or SSRI treatment was applied with satisfactory symptom control. Conclusions: After ruling out pheochromocytoma in patients presenting with paroxysmal hypertension, physicians should consider a diagnosis of pseudopheochromocytoma. Management of the disorder should include anxiolytic, antidepressant, a-adrenoceptor blockers, and b-adrenoceptor blockers treatment, with close cooperation between hypertension specialist and psychiatrist or psychologist. Early proper diagnosis can reduce emotional distress related to an extensive diagnostic process as well as the overall cost of healthcare in patients with pseudopheochromocytoma.
“…Good control of paroxysms in the third patient (who received anxiolytics treatment) speaks for diagnosis of ps-pheo. Given the proposed criteria the clinical features of the patients are suggestive of ps-pheo [5].…”
Section: Discussionmentioning
confidence: 99%
“…The panic disorder occurs in 12% of cases with hypertension [13] and shares similar symptoms with ps-pheo. However, what differentiates www.ah.viamedica.pl these conditions is that the latter is characterized by episodes of a significant increase in blood pressure in absence of any psychological triggers [5,14]. Subsequently, the patients presented in our cases do not fulfill the Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria for panic disorder [15].…”
Section: Discussionmentioning
confidence: 99%
“…PTSD is another trauma-related condition in which symptoms resemble those of ps-pheo; however, in patients with PTSD elevation of blood pressure is rarely seen [5]. Additionally, diagnosis of the PTSD requires at least 1 month of reported impairment in social, occupational, and other important areas of functioning [16].…”
Section: Discussionmentioning
confidence: 99%
“…After the episode patients usually experience fatigue [3]; blood pressure is normal or slightly increased between onsets [5]. Those symptoms usually raise suspicion of pheochromocytoma [1].…”
Section: Introductionmentioning
confidence: 99%
“…www.ah.viamedica.pl Ps-pheo is a diagnosis of exclusion as it requires further examination. Additionally, negative abdominal imaging for an adrenal tumor supports the diagnosis [5]. Differential diagnosis of ps-pheo includes panic disorder, post-traumatic stress disorder (PTSD), labile hypertension and others [5].…”
Background: Pseudopheochromocytoma is a condition that occurs more frequently than other diseases presenting with similar symptoms such as: paroxysmal hypertension, diaphoresis, pallor, palpitations. However, due to the lack of specific guidelines and awareness among physicians, it is widely underdiagnosed. Conventional antihypertensive treatment is ineffective in controlling symptoms which leads to decreased quality of life in patients affected by this disorder.
Case presentation:In our paper, we present three female patients with paroxysmal hypertension who were admitted to the Department of Endocrinology for an investigation of suspected pheochromocytoma. The biochemical findings and imaging carried out at the hospital ruled out the diagnosis of an adrenal tumor in all three of the patients. Given the proposed criteria the clinical features of the patients were suggestive of pseudopheochromocytoma. In all three cases, the anxiolytic or SSRI treatment was applied with satisfactory symptom control. Conclusions: After ruling out pheochromocytoma in patients presenting with paroxysmal hypertension, physicians should consider a diagnosis of pseudopheochromocytoma. Management of the disorder should include anxiolytic, antidepressant, a-adrenoceptor blockers, and b-adrenoceptor blockers treatment, with close cooperation between hypertension specialist and psychiatrist or psychologist. Early proper diagnosis can reduce emotional distress related to an extensive diagnostic process as well as the overall cost of healthcare in patients with pseudopheochromocytoma.
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