Pseudomonas stutzeri pneumonia and septicemia in a patient with multiple myeloma

Abstract

A case of septicemia caused by Pseudomonas stutzeri belonging to the unusual biotype Vb-3 in a patient with multiple myeloma is described. The origin of the septicemia was attributed to a community-acquired pneumonia. The bacteriology and pathogenicity of P. stutzeri are reviewed. Pseudomonas stutzeri is a ubiquitous gram-negative rod found in soil and water, the hospital environment, and various clinical specimens (7). Some 90 years ago, the bacterium was described as Bacillus denitrificans Il by Burri and Stutzer, who found the organism in soil, manure, canal

Influence of carbon source on pyrimidine synthesis in Pseudomonas mendocina

“…With respect to pyrimidine starvation studies, the carbon source glucose appeared to lessen regulation at the level of enzyme synthesis compared to what has been observed when succinate served as the carbon source. The regulation of the pyrimidine biosynthetic pathway by carbon source in P. mendocina appeared to differ from how carbon source influenced the control of pyrimidine biosynthesis in the closely-related species Pseudomonas stutzeri.Since clinical isolates of the two species classified within the Pseudomonas stutzeri DNA homology group have been found to be of medical importance (POTVLIEGE et al 1987, ARAGONE et al 1992, it would seem to be important to study the regulation of nucleic acid metabolism in the P. stutzeri DNA homology group member Pseudomonas mendocina (DE VOS and DE LEY 1983). More specifically, it was of interest to determine how carbon source affects the regulation of pyrimidine biosynthesis in P. mendocina.…”

“…Since clinical isolates of the two species classified within the Pseudomonas stutzeri DNA homology group have been found to be of medical importance (POTVLIEGE et al 1987, ARAGONE et al 1992, it would seem to be important to study the regulation of nucleic acid metabolism in the P. stutzeri DNA homology group member Pseudomonas mendocina (DE VOS and DE LEY 1983). More specifically, it was of interest to determine how carbon source affects the regulation of pyrimidine biosynthesis in P. mendocina.…”

MALDI-TOF MS for the Identification of Cultivable Organic-Degrading Bacteria in Contaminated Groundwater near Unconventional Natural Gas Extraction Sites

“…These findings were particularly interesting as, according to the literature, these two bacteria are usually found in the environment, specifically in soil and water [ 40 , 41 ]. In fact, P. stutzeri was previously identified in fluids used for hydraulic fracturing [ 14 ] and the authors suggested that this microorganism may be involved in the oxidation of alkane or aromatic compounds coupled to nitrate reduction.…”

“…Its source may be the water used as a constituent of the hydraulic fluid, which can originate from different sources, such as surface water, groundwater, or recycled flowback [ 14 ]. The identified bacteria are not life-threatening to humans, although some cases have been reported where P. stutzeri caused infection [ 40 , 41 , 42 , 43 ] and A. haemolyticus caused bloody diarrhea [ 44 , 45 ].…”

10-Years Hospital Experience in Pseudomonas stutzeri and Literature Review

“…Communityacquired infections caused by P. stutzeri have included pneumonia with empyema [11,12] and without empyema [13,14] including one case in a previously healthy child [15]. P. stutzeri has also been associated with septicemia [9,[16][17][18][19][20] and bacteremia [21], as well as endocarditis on a prosthetic mitral valve [22], and a case of endocarditis with relapse after several years [23]. Meningitis due to P. stutzeri has also been described [24][25][26].…”